Evidence map›Paper›PMID 32998702›Full record

ArticleBMC cancer2020

Quantifying the under-estimation of cervical Cancer in remote regions of Tanzania.

Mariah P Gesink, Robert M Chamberlain, Julius Mwaiselage, Crispin Kahesa, Kahima Jackson, William Mueller, Jane L Meza, Amr S Soliman

Open access · goldAbstract read
In one paragraph

Article in BMC cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 2 countries.

Mariah P GesinkCollege of Public Health, University of Nebraska Medical School, Omaha, NE, USA.
Robert M ChamberlainCity University of New York Medical School, 160 Convent Avenue, New York, NY, 10031, USA.
Julius MwaiselageOcean Road Cancer Institute, Dar es Salaam, Tanzania.
Crispin KahesaOcean Road Cancer Institute, Dar es Salaam, Tanzania.
Kahima JacksonBugando Hospital, Mwanza, Tanzania.
William MuellerMbeya Referral Hospital, Mbeya, Tanzania.
Jane L MezaCollege of Public Health, University of Nebraska Medical School, Omaha, NE, USA.
Amr S SolimanCity University of New York Medical School, 160 Convent Avenue, New York, NY, 10031, USA. asoliman@med.cuny.edu.ORCID http://orcid.org/0000-0003-2284-360X
Ocean Road Cancer Institute · TZUniversity of Nebraska Medical Center · USBugando Medical Centre · TZCity College of New York · USMbeya University of Science and Technology · TZThe University of Texas MD Anderson Cancer Center · US

Funding

Cancer Epidemiology Education in Special Populations Program-15R25CA112383 · NCI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI Amr Soliman · 2006 to 2026
$6.1M
NCI NIH HHS R25 CA112383
6 · The paper itself

Abstract

backgroundCervical cancer is the most common cancer among women in Sub-Saharan countries, including Tanzania. While early detection and diagnosis are available in some parts of this large country, radiotherapy has been only available at the Ocean Road Cancer Institute (ORCI), in the capital city of Dar es Salaam and is just starting in a few regions.

methodsThe objective of this study was to compare the observed incidence of cervical cancer for the two remote regions of Mwanza in western Tanzania and Mbeya in southern Tanzania, based on their patients treated at the ORCI from 2011 to 2014.

resultsThe number patients referred and treated at ORCI were (120 from Mwanza, and 171 from Mbeya, representing 24.6 and 32.8% of the patients histopathologically confirmed in the two sites, respectively. The results showed significant underestimation of cervical cancer in the two regions. The vast majority of patients who were histopathologically-confirmed in their local regions (73.92% from Mwanza and 65.1% from Mbeya), but did not receive the needed radiotherapy treatment at the ORCI. The estimated incidence for the two regions based on the number of patients treated at the ORCI were underestimated by 53.9% for Mwanza and 68.9% for Mbeya.

conclusionsLocal establishment of radiotherapy treatment facilities in remote regions in Tanzania and similar other low-income countries is essential for providing effective treatment and improving survival of diagnosed cervical cancer patients. Linkage between the records of local remote hospitals and the main cancer treatment center in the capital city can also help support the emerging the population-based cancer registry at ORCI.

Indexed as

Early Detection of CancerHealth Knowledge, Attitudes, PracticeAdolescentAdultAfrica, NorthernFemaleHumansIncidenceMiddle AgedPovertyTanzaniaUterine Cervical NeoplasmsYoung AdultCervical cancerEpidemiologyExpectedIncidenceObservedTanzania

Identifiers

PMID32998702
PMCPMC7526175
OpenAlexW3091292144

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.