Evidence map›Paper›PMID 32998289›Full record

ReviewBiomolecules2020

Omics-Based Platforms: Current Status and Potential Use for Cholangiocarcinoma.

Yu-Chan Chang, Ming-Huang Chen, Chun-Nan Yeh, Michael Hsiao

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Biomolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Prognostic value ofWorld journal of gastrointestinal oncology · 2024
    Article
  2. Review
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Yu-Chan ChangDepartment of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei 112, Taiwan.ORCID 0000-0003-0474-9935
Ming-Huang ChenSchool of Medicine, National Yang-Ming University, Taipei 112, Taiwan.ORCID 0000-0003-3187-7393
Chun-Nan YehDepartment of General Surgery, Liver Research Center, Chang Gung Memorial Hospital, Linkou, Taoyuan 333, Taiwan.
Michael HsiaoGenomics Research Center, Academia Sinica, 128 Academia Rd., Sec. 2, Nankang-Dist., Taipei 115, Taiwan.ORCID 0000-0001-8529-9213
National Yang Ming Chiao Tung University · TWChang Gung Memorial Hospital · TWGenomics Research Center, Academia Sinica · TW

Funding

Academia Sinica AS-SUMMIT-108, AS-SUMMIT-109, ASKPQ-109-BioMedChang Gung Memorial Hospital CORPG3J0251~2, CMRPG3I0241~2, CRRPG3K0011, CRRPG3K0031, CMRPG3K0711Ministry of Science and Technology MOST-108-3114-Y-001-002, MOST 107-2320-B-001 -016 -MY3
6 · The paper itself

Abstract

Cholangiocarcinoma (CCA) has been identified as a highly malignant cancer that can be transformed from epithelial cells of the bile duct, including intrahepatic, perihilar and extrahepatic. High-resolution imaging tools (abdominal ultrasound, computed tomography and percutaneous transhepatic cholangial drainage) are recruited for diagnosis. However, the lack of early diagnostic biomarkers and treatment evaluation can lead to serious outcomes and poor prognosis (i.e., CA19-9, MUC5AC). In recent years, scientists have established a large number of omics profiles to reveal underlying mechanisms and networks (i.e., IL-6/STAT3, NOTCH). With these results, we achieved several genomic alteration events (i.e., TP53

Indexed as

Antineoplastic AgentsBile Duct NeoplasmsBiomarkers, TumorCell Cycle ProteinsCholangiocarcinomaEpigenesis, GeneticGenomicsHumansMicroRNAsSmall Molecule LibrariesAntineoplastic AgentsBiomarkers, TumorCell Cycle ProteinsMicroRNAsSmall Molecule Librariescholangiocarcinomagenomic alterationsmetabolitesomicssmall molecule compounds/drugs

Identifiers

PMID32998289
PMCPMC7600697
OpenAlexW3088959642

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.