Evidence map›Paper›PMID 32998286›Full record

ArticleMarine drugs2020

Astaxanthin Inhibits p70 S6 Kinase 1 Activity to Sensitize Insulin Signaling.

Chunmei Li, Bixia Ma, Junhong Chen, Yoonhwa Jeong, Xiulong Xu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Marine drugs, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Chunmei LiCollege of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.
Bixia MaCollege of Food Science and Engineering, Yangzhou University, Yangzhou 225009, China.
Junhong ChenInstitute of Animal Science and Technology, Jinling Institute of Technology, Nanjing 211169, China.
Yoonhwa JeongResearch Center for Industrialization of Natural Nutraceuticals, Dankook University, Cheonan 31116, Korea.
Xiulong XuCollege of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.ORCID 0000-0001-6140-5173
Yangzhou University · CNDankook University · KRJinling Institute of Technology · CN

Funding

National Natural Science Foundation of China 3180010442National Natural Science Foundation of China 81672643
6 · The paper itself

Abstract

Astaxanthin (AST) is a carotenoid with therapeutic values on hyperglycemia and diabetic complications. The mechanisms of action of AST remain incompletely understood. p70 S6 kinase 1 (S6K1) is a serine/threonine kinase that phosphorylates insulin receptor substrate 1 (IRS-1)

Indexed as

3T3-L1 CellsAdipocytesAnimalsCell LineInsulinInsulin Receptor Substrate ProteinsInsulin ResistanceMiceMolecular Targeted TherapyMuscle Fibers, SkeletalPhosphorylationRatsReceptor, InsulinRibosomal Protein S6 Kinases, 70-kDaSignal TransductionXanthophyllsastaxanthineInsulinInsulin Receptor Substrate ProteinsReceptor, Insulinribosomal protein S6 kinase, 70kD, polypeptide 1Ribosomal Protein S6 Kinases, 70-kDaXanthophyllsAKTastaxanthinglucose uptakeGLUT4insulin receptorPI-3 kinaseS6K1

Identifiers

PMID32998286
PMCPMC7600478
OpenAlexW3088404719

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.