ArticleJournal of clinical medicine2020
Risk Factors of Periprosthetic Infection in Patients with Tumor Prostheses Following Resection for Musculoskeletal Tumor of the Lower Limb.
Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 22 citations in OpenAlex.
- Analysis of the Relationship Between Survival and Postoperative Infection in Patients With Osteosarcoma.Journal of surgical oncology · 2026Article
- Limb-Salvage Reconstruction of the Proximal Humerus Using Patient-Specific 3D-Printed PEEK Implants: A Midterm Clinical Study.Bioengineering (Basel, Switzerland) · 2026Article
- Megaprosthetic Reconstruction for Pathological Proximal Humerus Fractures: Infection Rates, Prevention Strategies, and Functional Outcomes-A Narrative Review.Journal of clinical medicine · 2025Review
- Periprosthetic Infection after Endoprosthetic Reconstruction for Femoral Bone Metastases: Incidence and Risk Factors, a Single Center Study.Clinics in orthopedic surgery · 2025Article
- A Novel Technique of Hip Disarticulation with a Stump with Soft Tissue of the Proximal Thigh: A Case Report.JBJS case connector · 2025Article
- Risk factors for peri-megaprosthetic joint infections in tumor surgery: A systematic review.SICOT-J · 2024Article
- Reducing the prosthesis modulus by inclusion of an open space lattice improves osteogenic response in a sheep model of extraarticular defect.Frontiers in bioengineering and biotechnology · 2023Article
- Postoperative clinical and functional outcomes in patients with tumor and tumor-like lesion of foot and ankle.Journal of foot and ankle research · 2022Article
- Surgical Site Infection after Bone Tumor Surgery: Risk Factors and New Preventive Techniques.Cancers · 2022Review
- The Management of an Open Biopsy Tract Site Infection and Ulceration in the Setting of Osteosarcoma.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2022Article
- Evaluation of tumor-prostheses over time: Complications, functional outcome, and comparative statistical analysis after resection and reconstruction in orthopedic oncologic conditions in the lower extremities.SAGE open medicine · 2022Article
- The risk for complications and reoperations with the use of mega prostheses in bone reconstructions.Journal of orthopaedic surgery and research · 2021Observational
- Prosthetic Joint Infection: Updates on Prevention, Diagnosis and Therapy.Journal of clinical medicine · 2020Article
- Article
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
Abstract
Tumor prostheses for the lower limb following resection of musculoskeletal tumors is useful limb salvage management; however, as compared with routine total joint replacement, an increased incidence of deep periprosthetic infection of tumor prosthesis has been observed. The risk factors for periprosthetic infection of tumor prosthesis remain unclear. This study examines the risk factors and outcomes of periprosthetic infection. This was a retrospective observational study including 121 patients (67 males and 54 females) who underwent tumor prosthesis of the lower limb after resection of musculoskeletal tumors between 1 January 2000 and 30 November 2018. Among a total of 121 tumor prostheses, 7 were total femurs, 47 were proximal femurs, 47 were distal femurs, and 20 were proximal tibias. The incidence of postoperative infection and its risk factors were analyzed. Forty-five patients (37%) had osteosarcoma, 36 patients (30%) had bone metastasis, and 10 patients (8%) had soft-tissue tumors invading the bone. The mean operating time was 229 min, and the mean follow-up duration was 5.9 years. Deep periprosthetic infection was noted in 14 patients (12%). In the multivariate analysis, the risk factors for postoperative infection were identified as being male (hazard ratio [HR], 11.2316;
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Registered trials
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