Evidence map›Paper›PMID 32998201›Full record

ArticlePathogens (Basel, Switzerland)2020

A New Type of Chronic Wound Infection after Wisdom Tooth Extraction: A Diagnostic Approach with 16S-rRNA Gene Analysis, Next-Generation Sequencing, and Bioinformatics.

Sebastian Böttger, Silke Zechel-Gran, Philipp Streckbein, Michael Knitschke, Torsten Hain, Markus Weigel, Jan-Falco Wilbrand, Eugen Domann, Hans-Peter Howaldt, Sameh Attia

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04791436 (Oral and Olfactory Complications of Recovered COVID-19 Patients), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04791436 unknown statusnot on this mapstarted 2021, after this paper: background citation

Oral and Olfactory Complications of Recovered COVID-19 Patients: A Prospective Cohort Study

TypeobservationalSponsorUniversity of GiessenRan2021 to 2025Enrolled402ConditionsOral Complication, Dysgeusia, Olfactory DisorderArmsGustatory and olfactory function test, Molecular assessment of saliva
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. New microbes and new infections · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Sebastian BöttgerDepartment of Oral and Maxillofacial Surgery, Justus-Liebig-University Giessen, University Hospital Giessen and Marburg, Location Giessen, Klinikstrasse 33, D-35392 Giessen, Germany.
Silke Zechel-GranInstitute of Medical Microbiology, Justus-Liebig-University Giessen, Biomedical Research Facility Seltersberg (BFS), Schubertstrasse 81, D-35392 Giessen, Germany.
Philipp StreckbeinDepartment of Oral and Maxillofacial Surgery, Justus-Liebig-University Giessen, University Hospital Giessen and Marburg, Location Giessen, Klinikstrasse 33, D-35392 Giessen, Germany.ORCID 0000-0003-0113-1128
Michael KnitschkeDepartment of Oral and Maxillofacial Surgery, Justus-Liebig-University Giessen, University Hospital Giessen and Marburg, Location Giessen, Klinikstrasse 33, D-35392 Giessen, Germany.
Torsten HainInstitute of Medical Microbiology, Justus-Liebig-University Giessen, Biomedical Research Facility Seltersberg (BFS), Schubertstrasse 81, D-35392 Giessen, Germany.
Markus WeigelInstitute of Medical Microbiology, Justus-Liebig-University Giessen, Biomedical Research Facility Seltersberg (BFS), Schubertstrasse 81, D-35392 Giessen, Germany.ORCID 0000-0002-3140-3174
Jan-Falco WilbrandDepartment for Cranio-Maxillofacial Surgery-Plastic Surgery, Diakonie Klinikum Jung-Stilling, Wichernstr. 40, D-57074 Siegen, Germany.ORCID 0000-0003-1081-6057
Eugen DomannInstitute of Medical Microbiology, Justus-Liebig-University Giessen, Biomedical Research Facility Seltersberg (BFS), Schubertstrasse 81, D-35392 Giessen, Germany.
Hans-Peter HowaldtDepartment of Oral and Maxillofacial Surgery, Justus-Liebig-University Giessen, University Hospital Giessen and Marburg, Location Giessen, Klinikstrasse 33, D-35392 Giessen, Germany.
Sameh AttiaDepartment of Oral and Maxillofacial Surgery, Justus-Liebig-University Giessen, University Hospital Giessen and Marburg, Location Giessen, Klinikstrasse 33, D-35392 Giessen, Germany.ORCID 0000-0002-9174-6435
Justus-Liebig-Universität Gießen · DEDiakonie Klinikum Jung-Stilling · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Delayed-onset infections are rare postoperative complications of lower third molar extractions. This article presents a case of a chronic combined hard and soft tissue infection after the extraction of a third molar, where the causative organisms could only be elucidated by molecular methods. Experimental 16S-rRNA gene analysis with next-generation sequencing and bioinformatics was used to identify the bacterial spectrum of the infection. 16S-rRNA gene analysis delivered the microbiome of the abscessing inflammation while standard culture and laboratory examinations were all sterile. The microbiome showed a mixed bacterial infection with a dominance of

Indexed as

16S-rRNA gene analysisenvironmental bacteriapostoperative wound infectionthird molar surgery

Identifiers

PMID32998201
PMCPMC7601215
OpenAlexW3088268715

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.