ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2021
Depression, anxiety, and loneliness among adolescents and young adults with IBD in the UK: the role of disease severity, age of onset, and embarrassment of the condition.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 3 of them syntheses that pooled it.
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Who cites it
30 citing papers in PubMed, 3 syntheses or guidelines pooled it, 53 citations in OpenAlex.
- Measures of identity in adolescents/young adults with long-term physical health conditions: a systematic review.Journal of pediatric psychology · 2026Pooled it
- Relationship between diet quality and inflammatory bowel disease: a systematic review of observational studies.BMC gastroenterology · 2025Pooled it
- Vitamin D Supplementation and Mental Health in Inflammatory Bowel Diseases and Irritable Bowel Syndrome Patients: A Systematic Review.Nutrients · 2021Pooled it
- "Being a light at the end of the tunnel": Peer mentor experiences on supporting adolescents with inflammatory bowel disease.Journal of pediatric psychology · 2026Article
- Exploring the Power of Peer-Related Social Factors in Mediating the Effects of Pain on Loneliness and Stress in Adolescents.European journal of pain (London, England) · 2026Article
- Health Mindset in Pediatric Inflammatory Bowel Disease: Exploring the Relationship Between Health Mindset and Key Physical and Psychosocial Outcomes.Children (Basel, Switzerland) · 2026Article
- Illness experience and coping strategies of young adults with inflammatory bowel disease: a qualitative study.Frontiers in pediatrics · 2026Article
- The relationship between diet quality index (DQI) with inflammatory indices and body mass index (BMI) in inflammatory bowel disease (IBD) patients.Scientific reports · 2025Article
- Analysis of global burden of inflammatory bowel disease among adolescents and young adults from 1990 to 2021 and projections to 2040.BMC public health · 2025Article
- Adolescent and caregiver perceptions of addressing mental health in inflammatory bowel disease.Journal of child health care : for professionals working with children in the hospital and community · 2025Article
- Understanding diagnostic delays and health outcomes for inflammatory bowel disease: a mixed-methods study of patients' perspectives.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- Reflections on youth partnership in a randomized controlled trial of an intervention to optimize transition from pediatric to adult care in inflammatory bowel disease.Health care transitions · 2025Article
- Reactions, Reality, and Resilience in Adults with Crohn's Disease: A Qualitative Study.Crohn's & colitis 360 · 2025Article
- Peer-support needs and experiences of young adults with chronic conditions: A mixed methods study.Health care transitions · 2025Article
- Bolstering connectedness through peer support: Randomized-controlled trial of a web-based peer support program for adolescents with inflammatory bowel disease.Health care transitions · 2025Article
- The Relationship Between Loneliness, Social Isolation, and Inflammatory Bowel Disease: A Narrative Review.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2024Review
- Comprehensive analysis of psychological symptoms and quality of life in early patients with IBD: a multicenter study from China.BMC psychiatry · 2024Article
- Shyness, Sport Engagement, and Internalizing Problems in Chinese Children: The Moderating Role of Class Sport Participation in a Multi-Level Model.Behavioral sciences (Basel, Switzerland) · 2024Article
- Perceptions of and Experiences with the COVID-19 Pandemic Among Individuals with Inflammatory Bowel Disease.Journal of clinical psychology in medical settings · 2024Article
- Burden of Anxiety, Depression and Perceived Stress in Patients with Inflammatory Bowel Disease: A Cohort Study from North India.Digestive diseases and sciences · 2024Article
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 2 countries.
Funding
Abstract
purposeAdolescents and young adults (AYA) with Inflammatory Bowel Disease (IBD) report higher depressive symptoms and anxiety compared to healthy controls, with disease severity and abdominal pain being important factors. In the current study, building on what young people had told us in our previous work, we examined whether embarrassment of the condition, social self-efficacy, and friendship quality mediated the relationship between abdominal pain and disease severity, and mental health/well-being. We also included loneliness as a component of well-being.
methodsData on depression, anxiety, loneliness, friendship quality, social self-efficacy, and disease embarrassment were collected from 130 AYA with IBD ages 14-25 years; data on disease severity and abdominal pain were taken from their medical records. Structural Equation Modeling (SEM) was used to test the relationships between the variables.
resultsUsing SEM, we established that higher IBD disease activity negatively impacted how AYA felt about their friendships and how embarrassed they were about their condition; embarrassment then influenced reports of mental health, including loneliness. Abdominal pain, disease onset, and social self-efficacy directly predicted internalising problems.
conclusionIn this sample of 14-25-year-old patients with IBD, specifics about the disease (severity and pain) predicted poorer mental health, suggesting discussion of mental health should be part of the clinical dialogue between patient and consultant. In addition, embarrassment about their condition increased depression, anxiety, and loneliness, mediating the relationship between disease severity and well-being. Thus, it is important to consider how perceived stigma affects those with chronic illness, and those issues should be explored in clinic.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.