ArticleEnvironmental science and pollution research international2021
Toxic effect of some heavy metals on hematology and histopathology of major carp (Catla catla).
Article in Environmental science and pollution research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 111 citations in OpenAlex.
- Integrated Biomarker Assessment of Bifenthrin, Chlorpyrifos and Endosulfan Toxicity in Indigenous Carps (Catla catla and Labeo rohita): Oxidative Stress, Genotoxicity and Nuclear Alterations.Veterinary medicine and science · 2026Article
- Cadmium-induced changes in haemato-immunological, oxidative stress and antioxidant parameters of Cyprinus carpio: Protective role of curcumin.Journal of fish biology · 2026Article
- Fenugreek seed extract supplementation: a mitigating strategy against tannery effluent toxicity in Catla catla.Veterinary research communications · 2026Article
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- The effects of the heavy metals cadmium and lead on six metabolic and immune-related enzymes in the loachPeerJ · 2026Article
- Integrating hematological profile and biomarker analysis for metals and metalloids ecotoxicological assessment on Wallago catfish and Indian carp health in Head Siphon, Mailsi, Pakistan.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2025Article
- Trace elements in fish species from the Punjnad headworks: Bioaccumulation and human health risk assessment.PloS one · 2025Article
- Toxic Effects of Cadmium Exposure on Hematological and Plasma Biochemical Parameters in Fish: A Review.Toxics · 2024Review
- Combined effect of endophytic Bacillus mycoides and rock phosphate on the amelioration of heavy metal stress in wheat plants.BMC plant biology · 2024Article
- Review
- Copper sulfate induces clinico-hematological, oxidative stress, serum biochemical and histopathological changes in freshwater fish rohu (Frontiers in veterinary science · 2023Article
- Toxic Effects of Cadmium on Fish.Toxics · 2022Review
- The antioxidant defense capacities and histological alterations in the livers and gills of two fish species, Oreochromis niloticus and Clarias gariepinus, as indicative signs of the Batts drain pollution.Environmental science and pollution research international · 2022Article
- Effects of bisphenol a on hematological, serum biochemical, and histopathological biomarkers in bighead carp (Aristichthys nobilis) under long-term exposure.Environmental science and pollution research international · 2022Article
- Biomarker-assisted assessment of aquatic health using the cosmopolitan common carp, Cyprinus carpio (L): a case study of bisphenol-A exposures.Environmental science and pollution research international · 2022Article
- Nuclear and Morphological Alterations in Erythrocytes, Antioxidant Enzymes, and Genetic Disparities Induced by Brackish Water in Mrigal Carp (Oxidative medicine and cellular longevity · 2022Article
- Acetochlor Affects Bighead Carp (BioMed research international · 2022Article
- Clinicohematological, Mutagenic, and Oxidative Stress Induced by Pendimethalin in Freshwater Fish Bighead Carp (Oxidative medicine and cellular longevity · 2022Article
- Bisphenol A induced toxicity in blood cells of freshwater fishSaudi journal of biological sciences · 2021Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The current study was conducted to assess the hematological and histopathological changes in major carp (Catla catla) exposed to different concentrations of copper (Cu) and cadmium (Cd). For this purpose, Catla catla fish, weighing approximately 230-235 g, were randomly divided into four groups and then exposed to acute doses of Cu (1.25 ppm), Cd (4.5 ppm), and their mixture (2.25 ppm) for 96 h and then 20, 30, and 40% respectively for a period of 30 days. Results showed that red blood cells (RBCs), hemoglobin (Hb), hematocrit (Hct), lymphocyte, and monocyte decreased significantly, while the total white blood cell count and neutrophil population significantly increased in experimental groups as compared with the control one. Histopathological examination of liver tissues showed karyorrhexis, hepatic cells degeneration, congestion, and hemorrhages. Microscopic analysis of gills' sections revealed lamellar atrophy, telangiectasia, and necrosis of lamellar epithelial cells. In the kidneys, different histopathological ailments like atrophy of glomeruli, necrosis of renal tubular cells, increased urinary spaces, degeneration of renal tubules, and melanomacrophage aggregates were observed, while in the intestine, atrophy of villi, sloughing of epithelial villi, and congestion were seen after 30 days of exposure. In conclusion, the study indicates that exposure to Cu and Cd for longer period of time causes adverse hematological and histopathological changes in Catla catla fish.
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