Evidence map›Paper›PMID 32997181›Full record

ArticleEuropean radiology2021

Dynamic contrast-enhanced magnetic resonance imaging biomarkers predict chemotherapeutic responses and survival in primary central-nervous-system lymphoma.

Fan Fu, Xuefei Sun, Yingying Li, Yuanbo Liu, Yi Shan, Nan Ji, Xiaochen Wang, Jie Lu, Shengjun Sun

Abstract read
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In one paragraph

Article in European radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Fan FuDepartment of Radiology, Xuanwu Hospital, Capital Medical University, No. 45 Changchun Street, Xicheng District, Beijing, 100053, China.
Xuefei SunDepartment of Hematology, Beijing Tiantan Hospital, Capital Medical University, No. 119 Nansihuan Road, Fengtai District, Beijing, 100070, China.
Yingying LiDepartment of Neuroradiology, Beijing Tiantan Hospital, No. 119 Nansihuan Road, Fengtai District, Beijing, 100070, China.
Yuanbo LiuDepartment of Hematology, Beijing Tiantan Hospital, Capital Medical University, No. 119 Nansihuan Road, Fengtai District, Beijing, 100070, China.
Yi ShanDepartment of Radiology, Xuanwu Hospital, Capital Medical University, No. 45 Changchun Street, Xicheng District, Beijing, 100053, China.
Nan JiDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, No. 45 Changchun Street, Xicheng District, Beijing, 100070, China.
Xiaochen WangDepartment of Neuroradiology, Beijing Tiantan Hospital, No. 119 Nansihuan Road, Fengtai District, Beijing, 100070, China.
Jie LuDepartment of Radiology, Xuanwu Hospital, Capital Medical University, No. 45 Changchun Street, Xicheng District, Beijing, 100053, China. imaginglu@hotmail.com.
Shengjun SunNeuroradiology Department, Beijing Neurosurgical Institute, No. 45 Changchun Street, Xicheng District, Beijing, 100070, China. sunshengjun0212@163.com.ORCID http://orcid.org/0000-0001-5024-145X

Funding

Beijing Municipal Administration of Hospitals Ascent Plan DFL20180802Capital's Funds of Health Improvement and Research 2018-2-1074National Natural Science Foundation of China 81971614
6 · The paper itself

Abstract

objectivesTo evaluate the utility of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) in predicting the response of chemotherapy and clinical outcomes in primary central-nervous-system lymphoma (PCNSL) patients.

methodsDCE-MRI in 56 patients enrolled in a prospective study was performed at baseline and 30 days after treatment from 2016 to 2019. Multivariate logistic regression analyses were performed to assess risk factors for tumor responses. The predictive values of related parameters derived from DCE were analyzed via receiver operating characteristic (ROC) curve analysis. To evaluate prognostic factors, the Kaplan-Meier survival analysis with log-rank tests and Cox regression tests were analyzed.

resultsK

conclusionsK KEY POINTS: • Baseline K

Indexed as

Central Nervous System NeoplasmsContrast MediaBiomarkersHumansMagnetic Resonance ImagingProspective StudiesTumor MicroenvironmentBiomarkersContrast MediaBiomarkersLymphomaMagnetic resonance imagingPrognosisSurvival

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.