SynthesisInternational journal of public health2020
Neonatal sepsis and its associated factors in East Africa: a systematic review and meta-analysis.
Synthesis in International journal of public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 4 of them syntheses that pooled it.
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Who cites it
23 citing papers in PubMed, 4 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- Prevalence and factors associated with maternal and neonatal sepsis in sub-Saharan Africa: a systematic review and meta-analysis.Frontiers in public health · 2024Pooled it
- Pooled it
- Antenatal Care Reduces Neonatal Mortality in Ethiopia: A Systematic Review and Meta-Analysis of Observational Studies.Maternal and child health journal · 2023Pooled it
- Neonatal sepsis and its associated factors in East Africa: a systematic review and meta-analysis.International journal of public health · 2020Pooled it
- Article
- Prevalence and risk factors of neonatal sepsis in the neonatal intensive care unit at Soroti Regional Referral hospital, Uganda: a retrospective study.BMC pregnancy and childbirth · 2025Article
- Bacteriological profile and antibiotic susceptibility of early-onset neonatal bacterial infection in a neonatal unit in Cameroon.BMC pediatrics · 2025Article
- Prevalence and factors associated with poor umbilical cord care among postpartum mothers in South Western Uganda: a cross sectional study.BMC pediatrics · 2025Article
- Investigation of methicillin, beta lactam, carbapenem, and multidrug resistant bacteria from blood cultures of septicemia suspected patients in Northwest Ethiopia.Scientific reports · 2025Article
- Prevalence and factors associated with neonatal sepsis in Mali: a cross-sectional study.BMJ open · 2025Article
- Neonatal Sepsis: Prevalence and Contributing Factors Among Neonates Admitted to the Special Care Unit at Kawempe National Referral Hospital, Kampala, Uganda.Clinical medicine insights. Pediatrics · 2025Article
- Predictors of Length of Hospitalization for Neonatal Sepsis at Kenyatta Nation Hospital, Kenya: A Prospective Cross-Sectional Study.Health science reports · 2025Article
- Neonatal sepsis and its predictors in Ethiopia: umbrella reviews of a systematic review and meta-analysis, 2023.Annals of medicine and surgery (2012) · 2024Review
- Magnitude and clinical characteristics of cerebral palsy among children in Africa: A systematic review and meta-analysis.PLOS global public health · 2024Article
- Bacterial profiles and their antibiotic susceptibility patterns in neonatal sepsis at the University of Gondar Comprehensive Specialized Hospital, Ethiopia.Frontiers in microbiology · 2024Article
- Cost-effectiveness analysis of Smart Triage, a data-driven pediatric sepsis triage platform in Eastern Uganda.BMC health services research · 2023Article
- Evaluation of the host immune response assay SeptiCyte RAPID for potential triage of COVID-19 patients.Scientific reports · 2023Article
- The utilization of clinical decision support tools to identify neonatal hypothermia and its associated risk factors: A prospective observational study.PLOS global public health · 2023Article
- Clinical Prediction Model Development and Validation for the Detection of Newborn Sepsis, Diagnostic Research Protocol.International journal of general medicine · 2022Article
- Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThis systematic review and meta-analysis aimed to reveal the magnitude of neonatal sepsis and its associated factors in East Africa.
methodsUsing PRISMA guideline, we reviewed and meta-analyzed studies from Google Scholar, Cochrane library, and PubMed; last search date: October 15, 2019. Heterogeneity across the studies was estimated. The subgroup analysis was done. Publication bias was also assessed.
resultsA total of 26 studies with 11,239 participants are included. The pooled prevalence of neonatal sepsis in East Africa was 29.765% (95% CI 23.36-35.94). Home delivery (AOR = 2.67; 95% CI 1.15-4.00), maternal history of urinary tract infection (UTI) (AOR = 2.083; 95% CI 0.24-3.93), gestational age/(preterm) (AOR = 1.56; 95% CI 1.04-2.08), prolonged labor (AOR = 3.23; 95% CI 0.04-6.51) and PROM (AOR = 1.95; 95% CI 0.53-3.37) were identified associated factors of neonatal sepsis.
conclusionsThe prevalence of neonatal sepsis in East Africa remains high. The relevant stockholders should give attention for neonates delivered from women with intranatal fever to prevent neonatal sepsis. Pregnant women should be screened for UTI. Appropriate interventions should be put in place to manage PROM to decrease the chance of ascending microorganisms.
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