Evidence map›Paper›PMID 32996203›Full record

ReviewJournal of neuroendocrinology2020

Transcriptional regulation of prolactin in a euryhaline teleost: Characterisation of gene promoters through in silico and transcriptome analyses.

Andre P Seale, Gardi Hewage Tharindu Malintha, Fritzie T Celino-Brady, Tony Head, Mahdi Belcaid, Yoko Yamaguchi, Darren T Lerner, David A Baltzegar, Russell J Borski, Zoia R Stoytcheva and 1 more

Open access · greenAbstract readReview
In one paragraph

Review in Journal of neuroendocrinology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Osmosensitive transcription factors in the prolactin cell of a euryhaline teleost.Comparative biochemistry and physiology. Part A, Molecular & integrative physiology · 2023
    Article
  4. Tilapia prolactin cells are thermosensitive osmoreceptors.American journal of physiology. Regulatory, integrative and comparative physiology · 2022
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Andre P SealeDepartment of Human Nutrition, Food and Animal Sciences, University of Hawai'i at Mānoa, Honolulu, HI, USA.ORCID 0000-0003-2398-4201
Gardi Hewage Tharindu MalinthaDepartment of Human Nutrition, Food and Animal Sciences, University of Hawai'i at Mānoa, Honolulu, HI, USA.
Fritzie T Celino-BradyDepartment of Human Nutrition, Food and Animal Sciences, University of Hawai'i at Mānoa, Honolulu, HI, USA.
Tony HeadDepartment of Human Nutrition, Food and Animal Sciences, University of Hawai'i at Mānoa, Honolulu, HI, USA.
Mahdi BelcaidHawai'i Institute of Marine Biology, University of Hawai'i at Mānoa, Kaneohe, HI, USA.
Yoko YamaguchiInstitute of Agricultural and Life Sciences, Academic Assembly, Shimane University, Matsue, Japan.
Darren T LernerUniversity of Hawai'i Sea Grant College Program, University of Hawai'i at Mānoa, Honolulu, HI, USA.
David A BaltzegarGenomic Sciences Laboratory, Office of Research and Innovation, North Carolina State University, Raleigh, NC, USA.
Russell J BorskiDepartment of Biological Sciences, North Carolina State University, Raleigh, NC, USA.
Zoia R StoytchevaDepartment of Human Nutrition, Food and Animal Sciences, University of Hawai'i at Mānoa, Honolulu, HI, USA.
Jason P BrevesDepartment of Biology, Skidmore College, Saratoga Springs, NY, USA.ORCID 0000-0003-1193-4389
University of Hawaiʻi at Mānoa · USNorth Carolina State University · USShimane University · JPSkidmore College · US

Funding

Integrating Osmosensitivity and Autocrine Signaling in a Model for Osmoregulation.R21DK111775 · NIDDK · UNIVERSITY OF HAWAII AT MANOA · PI SEALE, ANDRE P. · 2016 to 2019
$459k
NIDDK NIH HHS 1R21DK111775-01NIDDK NIH HHS R21 DK111775
6 · The paper itself

Abstract

The sensitivity of prolactin (Prl) cells of the Mozambique tilapia (Oreochromis mossambicus) pituitary to variations in extracellular osmolality enables investigations into how osmoreception underlies patterns of hormone secretion. Through the actions of their main secretory products, Prl cells play a key role in supporting hydromineral balance of fishes by controlling the major osmoregulatory organs (ie, gill, intestine and kidney). The release of Prl from isolated cells of the rostral pars distalis (RPD) occurs in direct response to physiologically relevant reductions in extracellular osmolality. Although the particular signal transduction pathways that link osmotic conditions to Prl secretion have been identified, the processes that underlie hyposmotic induction of prl gene expression remain unknown. In this short review, we describe two distinct tilapia gene loci that encode Prl

Indexed as

AnimalsComputer SimulationGene Expression RegulationLactotrophsModels, GeneticOsmoregulationProlactinPromoter Regions, GeneticTilapiaTranscriptomeProlactinin silicoosmoreceptionprolactinpromotersalinitytilapiatranscription factortranscriptome

Identifiers

PMID32996203
PMCPMC8612711
OpenAlexW3082996662

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.