Evidence map›Paper›PMID 32995787›Full record

ArticlebioRxiv : the preprint server for biology2020

Functional genomic screens identify human host factors for SARS-CoV-2 and common cold coronaviruses.

Ruofan Wang, Camille R Simoneau, Jessie Kulsuptrakul, Mehdi Bouhaddou, Katherine Travisano, Jennifer M Hayashi, Jared Carlson-Stevermer, Jennifer Oki, Kevin Holden, Nevan J Krogan and 2 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Ruofan WangChan Zuckerberg Biohub, San Francisco, CA, 94158, USA.
Camille R SimoneauGladstone Institutes, San Francisco, CA 94158, USA.
Jessie KulsuptrakulChan Zuckerberg Biohub, San Francisco, CA, 94158, USA.
Mehdi BouhaddouGladstone Institutes, San Francisco, CA 94158, USA.
Katherine TravisanoChan Zuckerberg Biohub, San Francisco, CA, 94158, USA.
Jennifer M HayashiGladstone Institutes, San Francisco, CA 94158, USA.
Jared Carlson-StevermerSynthego Corporation, Menlo Park, CA 94025.
Jennifer OkiSynthego Corporation, Menlo Park, CA 94025.
Kevin HoldenSynthego Corporation, Menlo Park, CA 94025.
Nevan J KroganGladstone Institutes, San Francisco, CA 94158, USA.
Melanie OttGladstone Institutes, San Francisco, CA 94158, USA.
Andreas S PuschnikChan Zuckerberg Biohub, San Francisco, CA, 94158, USA.

Funding

SARS-CoV adaptations through a Systems Biology Lens (SYBIL)U19AI135972 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Adolfo Garcia-Sastre · 2018 to 2026
$27.2M
RESEARCH PROJECT 2U19AI135990 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Nevan J Krogan · 2018 to 2026
$21.4M
X-ray Screening and Rapid Structure DeterminationP50AI150476 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI STROUD, ROBERT M · 2019 to 2021
$14.4M
A new model of accelerated immune aging in HIV-infected drug usersDP1DA038043 · NIDA · J. DAVID GLADSTONE INSTITUTES · PI OTT, MELANIE MARIA · 2014 to 2019
$4.8M
Novel VP30-host Interactions that Negatively Regulate Ebola Virus InfectionR01AI143292 · NIAID · WASHINGTON UNIVERSITY · PI AMARASINGHE, GAYA K., BASLER, CHRISTOPHER F · 2019 to 2023
$4.0M
Discovery of novel, ubiquitin-regulated mechanisms of TB control by macrophagesR01AI120694 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI COX, JEFFERY S, KROGAN, NEVAN J · 2015 to 2019
$3.3M
Decoding the Chlamydia inclusion membrane protein-host protein interactomeR01AI122747 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ENGEL, JOANNE N., KAAKE, ROBYN MIDORI · 2016 to 2020
$3.1M
Systematic Targeting of Oncogene Interacting Proteins to Reveal New Therapeutic StrategiesF32CA239333 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BOUHADDOU, MEHDI · 2019 to 2021
$192k
NCI NIH HHS F32 CA239333NIAID NIH HHS P50 AI150476NIAID NIH HHS R01 AI120694NIAID NIH HHS R01 AI122747NIAID NIH HHS R01 AI143292NIAID NIH HHS U19 AI135972NIAID NIH HHS U19 AI135990NIDA NIH HHS DP1 DA038043
6 · The paper itself

Abstract

The

Identifiers

PMID32995787
PMCPMC7523113

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.