Evidence map›Paper›PMID 32995673›Full record

ArticleBioactive materials2021

Engineering of tissue constructs using coaxial bioprinting.

Andrew Kjar, Bailey McFarland, Keetch Mecham, Nathan Harward, Yu Huang

Abstract read
In one paragraph

Article in Bioactive materials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Thiolated Polymers in 3D Bioprinting: Control of Gelation.Advanced materials (Deerfield Beach, Fla.) · 2026
    Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. 3D-bioprinting for joint regeneration.Frontiers in bioengineering and biotechnology · 2026
    Review
  10. Review
  11. Review
  12. Review
  13. Review
  14. Review
  15. Review
  16. Article
  17. Article
  18. Engineering in vitro vascular microsystems.Microsystems & nanoengineering · 2025
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Andrew KjarDepartment of Biological Engineering, Utah State University, Logan, UT, 84322, USA.
Bailey McFarlandDepartment of Biological Engineering, Utah State University, Logan, UT, 84322, USA.
Keetch MechamDepartment of Biological Engineering, Utah State University, Logan, UT, 84322, USA.
Nathan HarwardDepartment of Biological Engineering, Utah State University, Logan, UT, 84322, USA.
Yu HuangDepartment of Biological Engineering, Utah State University, Logan, UT, 84322, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bioprinting is a rapidly developing technology for the precise design and manufacture of tissues in various biological systems or organs. Coaxial extrusion bioprinting, an emergent branch, has demonstrated a strong potential to enhance bioprinting's engineering versatility. Coaxial bioprinting assists in the fabrication of complex tissue constructs, by enabling concentric deposition of biomaterials. The fabricated tissue constructs started with simple, tubular vasculature but have been substantially developed to integrate complex cell composition and self-assembly, ECM patterning, controlled release, and multi-material gradient profiles. This review article begins with a brief overview of coaxial printing history, followed by an introduction of crucial engineering components. Afterward, we review the recent progress and untapped potential in each specific organ or biological system, and demonstrate how coaxial bioprinting facilitates the creation of tissue constructs. Ultimately, we conclude that this growing technology will contribute significantly to capabilities in the fields of in vitro modeling, pharmaceutical development, and clinical regenerative medicine.

Indexed as

3D bioprintingBiofabrication strategiesCoaxial nozzleRegenerative medicineTissue engineeringVascular constructs

Identifiers

PMID32995673
PMCPMC7490764

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.