Evidence map›Paper›PMID 32995672›Full record

ArticleBioactive materials2021

Inhibition of bacterial adhesion and biofilm formation by a textured fluorinated alkoxyphosphazene surface.

Meixian Tang, Chen Chen, Jieru Zhu, Harry R Allcock, Christopher A Siedlecki, Li-Chong Xu

Abstract read
In one paragraph

Article in Bioactive materials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Cyclo- and Polyphosphazenes for Biomedical Applications.Molecules (Basel, Switzerland) · 2022
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Meixian TangDepartment of Biomedical Engineering, The Pennsylvania State University, University Park, PA, 16802, United States.
Chen ChenDepartment of Chemistry, The Pennsylvania State University, University Park, PA, 16802, United States.
Jieru ZhuDepartment of Chemistry, The Pennsylvania State University, University Park, PA, 16802, United States.
Harry R AllcockDepartment of Chemistry, The Pennsylvania State University, University Park, PA, 16802, United States.
Christopher A SiedleckiDepartment of Biomedical Engineering, The Pennsylvania State University, University Park, PA, 16802, United States.
Li-Chong XuDepartment of Surgery, The Pennsylvania State University, College of Medicine, Hershey, PA, 17033, United States.

Funding

Textured Polyphosphazene Biomaterial with Improved HemocompatibilityR21AI139706 · NIAID · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI XU, LICHONG · 2018 to 2019
$412k
NIAID NIH HHS R21 AI139706
6 · The paper itself

Abstract

The utilization of biomaterials in implanted blood-contacting medical devices often induces a persistent problem of microbial infection, which results from bacterial adhesion and biofilm formation on the surface of biomaterials. In this research, we developed new fluorinated alkoxyphosphazene materials, specifically poly[bis(octafluoropentoxy) phosphazene] (OFP) and crosslinkable OFP (X-OFP), with improved mechanical properties, and further modified the surface topography with ordered pillars to improve the antibacterial properties. Three X-OFP materials, X-OFP

Indexed as

Anti-bacterial adhesionAnti-biofilmsCrosslinkingFluorinated polyphosphazeneMicrobial infectionTextured surface

Identifiers

PMID32995672
PMCPMC7490642

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.