Evidence map›Paper›PMID 32995566›Full record

ArticleInnovation in aging2020

Obstacle Negotiation in Older Adults: Prefrontal Activation Interpreted Through Conceptual Models of Brain Aging.

Sudeshna A Chatterjee, Rachael D Seidler, Jared W Skinner, Paige E Lysne, Chanoan Sumonthee, Samuel S Wu, Ronald A Cohen, Dorian K Rose, Adam J Woods, David J Clark

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Innovation in aging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Sudeshna A ChatterjeeDepartment of Physical Therapy, University of Florida, Gainesville.ORCID 0000-0002-7445-9717
Rachael D SeidlerDepartment of Applied Physiology and Kinesiology, University of Florida, Gainesville.
Jared W SkinnerGeriatric Research, Education, and Clinical Center, Malcom Randall VA Medical Center, Gainesville, Florida.
Paige E LysneDepartment of Aging and Geriatric Research, University of Florida, Gainesville.
Chanoan SumontheeCollege of Public Health and Health Professions, University of Florida, Gainesville.
Samuel S WuDepartment of Biostatistics, University of Florida, Gainesville.
Ronald A CohenDepartment of Clinical and Health Psychology, Center for Cognitive Aging and Memory, McKnight Brain Institute, University of Florida, Gainesville.
Dorian K RoseDepartment of Physical Therapy, University of Florida, Gainesville.
Adam J WoodsDepartment of Clinical and Health Psychology, Center for Cognitive Aging and Memory, McKnight Brain Institute, University of Florida, Gainesville.
David J ClarkBrain Rehabilitation Research Center, Malcom Randall VA Medical Center, Gainesville, Florida.ORCID 0000-0002-9921-1849
University of Florida · USMalcom Randall VA Medical Center · USUniversity of Florida Health · US

Funding

Combining tDCS and neurorehabilitation to treat age-related deficits of mobility and cognitionR21AG053736 · NIA · UNIVERSITY OF FLORIDA · PI CLARK, DAVID J · 2017 to 2018
$407k
NIA NIH HHS R21 AG053736
6 · The paper itself

Abstract

BACKGROUND AND

objectivesThe influence of interindividual differences on brain activation during obstacle negotiation and the implications for walking performance are poorly understood in older adults. This study investigated the extent to which prefrontal recruitment during obstacle negotiation is explained by differences in age, executive function, and sex. These data were interpreted according to the Compensation-Related Utilization of Neural Circuits Hypothesis (CRUNCH) framework of brain aging. We also tested the association between prefrontal recruitment and walking performance. RESEARCH DESIGN AND

methodsPrefrontal oxygenated hemoglobin concentration (O

resultsAge, executive function, and their interaction significantly predicted greater ∆PFR ( DISCUSSION AND IMPLICATIONS: These findings are consistent with the CRUNCH framework: neural inefficiency where a greater amount of brain activation is needed for task performance at a similar level, compensatory overactivation to prevent a steeper decline in task performance, and capacity limitation with a recruitment ceiling effect.

Indexed as

AgingComplex walkingExecutive functionNear-infrared spectroscopyPrefrontal cortex

Identifiers

PMID32995566
PMCPMC7508296
OpenAlexW3048669068

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.