Evidence map›Paper›PMID 32995481›Full record

ArticleMolecular therapy oncolytics2020

High Oncolytic Activity of a Double-Deleted Vaccinia Virus Copenhagen Strain against Malignant Pleural Mesothelioma.

Tiphaine Delaunay, Joelle Nader, Marion Grard, Isabelle Farine, Vera Hedwig, Johann Foloppe, Thibaut Blondy, Mathilde Violland, Daniel Pouliquen, Marc Grégoire and 3 more

Open access · goldAbstract read
In one paragraph

Article in Molecular therapy oncolytics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Oncolytic viruses: advanced strategies in cancer therapy.Signal transduction and targeted therapy · 2026
    Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Apoptosis during ZIKA Virus Infection: Too Soon or Too Late?International journal of molecular sciences · 2022
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Tiphaine DelaunayCRCINA, INSERM, Université d'Angers, Université de Nantes, 44007 Nantes, France.
Joelle NaderCRCINA, INSERM, Université d'Angers, Université de Nantes, 44007 Nantes, France.
Marion GrardCRCINA, INSERM, Université d'Angers, Université de Nantes, 44007 Nantes, France.
Isabelle FarineTransgene, 67400 Illkirch, France.
Vera HedwigTransgene, 67400 Illkirch, France.
Johann FoloppeTransgene, 67400 Illkirch, France.
Thibaut BlondyCRCINA, INSERM, Université d'Angers, Université de Nantes, 44007 Nantes, France.
Mathilde ViollandCRCINA, INSERM, Université d'Angers, Université de Nantes, 44007 Nantes, France.
Daniel PouliquenCRCINA, INSERM, Université d'Angers, Université de Nantes, 44007 Nantes, France.
Marc GrégoireCRCINA, INSERM, Université d'Angers, Université de Nantes, 44007 Nantes, France.
Nicolas BoisgeraultCRCINA, INSERM, Université d'Angers, Université de Nantes, 44007 Nantes, France.
Philippe ErbsTransgene, 67400 Illkirch, France.
Jean-François FonteneauCRCINA, INSERM, Université d'Angers, Université de Nantes, 44007 Nantes, France.
Transgene (France) · FRUniversité d'Angers · FRNantes Université · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malignant pleural mesothelioma (MPM) is a cancer of the pleura that lacks efficient treatment. Oncolytic immunotherapy using oncolytic vaccinia virus (VV) may represent an alternative therapeutic approach for the treatment of this malignancy. Here, we studied the oncolytic activity of VV thymidine kinase (

Indexed as

oncolytic immunotherapyoncolytic viruspleural mesotheliomaribonucleotide reductasethymidine kinasevaccinia virus

Identifiers

PMID32995481
PMCPMC7501423
OpenAlexW3082207775

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.