Evidence map›Paper›PMID 32995349›Full record

ArticleOpen forum infectious diseases2020

Limited Added Value of Oropharyngeal Swabs for Detecting Pneumococcal Carriage in Adults.

Jennifer L Farrar, Herine Odiembo, Arthur Odoyo, Godfrey Bigogo, Lindsay Kim, Fernanda C Lessa, Daniel R Feikin, Robert F Breiman, Cynthia G Whitney, Maria G Carvalho and 1 more

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. World Health Organization (WHO) Standard Methods for Pneumococcal Carriage Studies.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Jennifer L FarrarDivision of Bacterial Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Herine OdiemboGlobal Disease Detection Division (GDD) and International Emerging Infections Program (IEIP), Kenya Medical Research Institute (KEMRI)/CDC Public Health and Research Collaboration, Kisumu, Kenya.
Arthur OdoyoGlobal Disease Detection Division (GDD) and International Emerging Infections Program (IEIP), Kenya Medical Research Institute (KEMRI)/CDC Public Health and Research Collaboration, Kisumu, Kenya.
Godfrey BigogoGlobal Disease Detection Division (GDD) and International Emerging Infections Program (IEIP), Kenya Medical Research Institute (KEMRI)/CDC Public Health and Research Collaboration, Kisumu, Kenya.
Lindsay KimDivision of Bacterial Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Fernanda C LessaDivision of Bacterial Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Daniel R FeikinGlobal Disease Detection Division (GDD) and International Emerging Infections Program (IEIP), Kenya Medical Research Institute (KEMRI)/CDC Public Health and Research Collaboration, Kisumu, Kenya.
Robert F BreimanEmory Global Health Institute, Emory University, Atlanta, Georgia, USA.
Cynthia G WhitneyDivision of Bacterial Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Maria G CarvalhoDivision of Bacterial Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Fabiana C PimentaDivision of Bacterial Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Kenya Medical Research Institute · KENational Center for Immunization and Respiratory Diseases · USCenters for Disease Control and Prevention · USEmory University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We compared pneumococcal isolation rates and evaluated the benefit of using oropharyngeal (OP) specimens in addition to nasopharyngeal (NP) specimens collected from adults in rural Kenya. Of 846 adults, 52.1% were colonized; pneumococci were detected from both NP and OP specimens in 23.5%, NP only in 22.9%, and OP only in 5.7%. Ten-valent pneumococcal conjugate vaccine strains were detected from both NP and OP in 3.4%, NP only in 4.1%, and OP only in 0.7%. Inclusion of OP swabs increased carriage detection by 5.7%; however, the added cost of collecting and processing OP specimens may justify exclusion from future carriage studies among adults.

Indexed as

adultscarriagecolonizationnasopharyngealoropharyngealStreptococcus pneumoniae

Identifiers

PMID32995349
PMCPMC7505525
OpenAlexW3065645842

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.