Evidence map›Paper›PMID 32995323›Full record

ArticleAvicenna journal of phytomedicine

Evaluation of phytochemical and pharmacological properties of seeds of

Sumyya Zahan, Tajbiha-E- Mowla, S M Naim Uddin, Mohammed Kamrul Hossain, Afifa Binthe Mannan, Minhajur Rahman, Umay Chen, Tanoy Mazumder, A H M Mazbah Uddin, Sayema Arefin and 1 more

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in Avicenna journal of phytomedicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Antioxidants (Basel, Switzerland) · 2026
    Review
  2. Efficacy ofMetabolism open · 2025
    Review
  3. Potential effects and relevant lead compounds ofSaudi journal of biological sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Sumyya ZahanDepartment of Pharmacy, University of Chittagong, Chittagong-4331, Bangladesh.
Tajbiha-E- MowlaDepartment of Pharmacy, Southern University, Chittagong, Bangladesh.
S M Naim UddinDepartment of Pharmacy, University of Chittagong, Chittagong-4331, Bangladesh.
Mohammed Kamrul HossainDepartment of Pharmacy, University of Chittagong, Chittagong-4331, Bangladesh.
Afifa Binthe MannanDepartment of Genetic Engineering and Biotechnology, University of Chittagong, Chittagong-4331, Bangladesh.
Minhajur RahmanDepartment of Botany, University of Chittagong, Chittagong-4331, Bangladesh.
Umay ChenDepartment of Pharmacy, University of Chittagong, Chittagong-4331, Bangladesh.
Tanoy MazumderDepartment of Pharmacy, Noakhali Science and Technology University, Sonapur, Noakhali-3814, Bangladesh.
A H M Mazbah UddinDepartment of Pharmacy, Mawlana Bhashani Science and Technology University, Santosh-1902, Tangail.
Sayema ArefinDepartment of Pharmacy, Mawlana Bhashani Science and Technology University, Santosh-1902, Tangail.
Md Saddam HussainDepartment of Pharmacy, Noakhali Science and Technology University, Sonapur, Noakhali-3814, Bangladesh.
University of Chittagong · BDMawlana Bhashani Science and Technology University · BDNoakhali Science and Technology University · BDSouthern University · BD

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe purpose of the current study was to investigate the MATERIALS AND

methodsThe antioxidant property was evaluated by DPPH radical scavenging assay, while antimicrobial activity was examined against three Gram (+) and one Gram (-) bacteria. Thrombolytic and anthelmintic activities were evaluated by using human blood serum and by recording paralysis and death time in earthworm, respectively. Cytotoxic activity was investigated in brine shrimp nauplii. Analgesic and antidiarrheal activities were evaluated in Swiss albino mice and neurological effect was evaluated by open field and Elevated plus-maze test (EPM).

resultsAll fractions (n-hexane, carbon tetrachloride and chloroform) possess significant (p<0.05) cytotoxic activity. In case of thrombolytic activity, the highest concentration of methanolic extract produced a remarkable percentage of clot lysis (46.12%). The concentration of 1000 μg/ml produced a significant antibacterial activity against Gram positive

conclusionThe overall results of the study tend to suggest that the methanolic extract and its fractions have promising pharmacological activities.

Indexed as

In vitroIn vivoMomordica charantiaSeeds

Identifiers

PMID32995323
PMCPMC7508320
OpenAlexW3003299681

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.