Evidence map›Paper›PMID 32995307›Full record

ArticleMethodsX2020

Fabrication of high-quality glass microfluidic devices for bioanalytical and space flight applications.

Matin Golozar, Wai K Chu, Laura D Casto, Jeremy McCauley, Anna L Butterworth, Richard A Mathies

Abstract read
In one paragraph

Article in MethodsX, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Quantitative evaluation of the feasibility of sampling the ice plumes at Enceladus for biomarkers of extraterrestrial life.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Matin GolozarDepartment of Chemistry and Biophysics Graduate Group, University of California, Berkeley, CA 94720, United States.
Wai K ChuDepartment of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, United States.
Laura D CastoSpace Sciences Laboratory, University of California, 7 Gauss Way, Berkeley, CA 94720, United States.
Jeremy McCauleySpace Sciences Laboratory, University of California, 7 Gauss Way, Berkeley, CA 94720, United States.
Anna L ButterworthSpace Sciences Laboratory, University of California, 7 Gauss Way, Berkeley, CA 94720, United States.
Richard A MathiesDepartment of Chemistry and Biophysics Graduate Group, University of California, Berkeley, CA 94720, United States.

Funding

Shared Services Center NASA 80NSSC18K0600Shared Services Center NASA 80NSSC19K0600
6 · The paper itself

Abstract

Microfabricated glass microfluidic and Capillary Electrophoresis (CE) devices have been utilized in a wide variety of applications over the past thirty years. At the Berkeley Space Sciences Laboratory, we are working to further expand this technology by developing analytical instruments to chemically explore our solar system. This effort requires improving the quality and reliability of glass microfabrication through quality control procedures at every stage of design and manufacture. This manuscript provides detailed information on microfabrication technology for the production of high-quality glass microfluidic chips in compliance with industrial standards and space flight instrumentation quality control.•The methodological protocol provided in this paper includes the scope of each step of the manufacturing process, materials and technologies recommended and the specific challenges that often confront the process developer.•Types and sources of fabrication error at every stage have been identified and their solutions have been proposed and verified.•We present robust and rigorous manufacturing and quality control procedures that will assist other researchers in achieving the highest possible quality glass microdevices using the latest apparatus in a routine and reliable fashion.

Indexed as

AstrobiologyBiosignature detectionCapillary electrophoresisGlass microfabricationLab-on-a-chip

Identifiers

PMID32995307
PMCPMC7502335

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.