Evidence map›Paper›PMID 32995289›Full record

ArticleMolecular genetics and metabolism reports2020

Investigating the structural impacts of a novel missense variant identified with whole exome sequencing in an Egyptian patient with propionic acidemia.

Ali Zaki Ibrahim, D Thirumal Kumar, Taghreed Abunada, Salma Younes, C George Priya Doss, Osama K Zaki, Hatem Zayed

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular genetics and metabolism reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. NovelFrontiers in medicine · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Ali Zaki IbrahimFaculty of Medicine, Ain Shams University, Cairo, Egypt.
D Thirumal KumarSchool of BioSciences and Technology, Vellore Institute of Technology, Vellore, Tamil Nadu, India.
Taghreed AbunadaDepartment of Biomedical Sciences, College of Health Sciences, QU Health, Qatar University, Doha, Qatar.
Salma YounesDepartment of Biomedical Sciences, College of Health Sciences, QU Health, Qatar University, Doha, Qatar.
C George Priya DossSchool of BioSciences and Technology, Vellore Institute of Technology, Vellore, Tamil Nadu, India.
Osama K ZakiMedical Genetics Unit, Pediatric Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Hatem ZayedDepartment of Biomedical Sciences, College of Health Sciences, QU Health, Qatar University, Doha, Qatar.
Qatar University · QAAin Shams University · EGVellore Institute of Technology University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Propionic Acidemia (PA) is an inborn error of metabolism caused by variants in the

Indexed as

Computational analysisGenotype-phenotype correlationNext-generation sequencingPCCA genePropionic acidemia (PA)

Identifiers

PMID32995289
PMCPMC7502849
OpenAlexW3087161431

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.