ArticleJournal of acute medicine2017
Neuro-Preventive Effect and Elevation of Cellular Adenosine Triphosphate by PUFAs from Pteleiosis suberosa Stem Bark on Mercury Sub-Acute Exposed Rats.
Article in Journal of acute medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed, 1 citations in OpenAlex.
- A critical appraisal on the involvement of plant-based extracts as neuroprotective agents (2012-2022): an effort to ease out decision-making process for researchers.Naunyn-Schmiedeberg's archives of pharmacology · 2024Review
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesOccupational/industrial exposure and experimental intoxication of mercury can produce neurological effects but
methodsThe present study was therefore designed to investigate some phenolic constituents, evaluate its antioxidant properties and examine its reversal effects of PTSSBE on sub-acute mercury-induced brain toxicity. Rats were divided into five groups of 10 animals each. Group I was given distilled water; group II, III, IV and V was orally administered with mercury at a dose of 3.75 mg/kg body weight. Group III, IV and V were co-treated with PTSSBE of 25, 50 and 100 mg/ kg body weight respectively, for 10 days.
resultsThe results revealed that the stem bark extract exhibited high presence of antioxidants. Experimental exposure of rats to mercury significantly decreased the activities of catalase (CAT), lactate dehydrogenase (LDH), and the level of reduced glutathione (GSH), while the activities of alanine aminotransferase (ALT), aspartate aminotransferase (AST) and the formation of malondialdehyde (MDA) were increased. These effects were reversed by co-administration with PTSSBE in mercury-induced brain toxicity in rats.
conclusionThe protective effects of
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