ArticleJournal of acute medicine2020
The Use of Gray-White-Matter Ratios May Help Predict Survival and Neurological Outcomes in Patients Resuscitated From Out-of-Hospital Cardiac Arrest.
Article in Journal of acute medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 10 citations in OpenAlex.
- European Resuscitation Council and European Society of Intensive Care Medicine guidelines 2025: post-resuscitation care.Intensive care medicine · 2025Guideline
- The effect of the head-up position on cardiopulmonary resuscitation: a systematic review and meta-analysis.Critical care (London, England) · 2021Pooled it
- Gray-white matter ratio in pediatric and adult cardiopulmonary arrest studies: a rapid review.Resuscitation plus · 2026Review
- Combination of Cerebral Computed Tomography and Simplified Cardiac Arrest Hospital Prognosis (sCAHP) Score for Predicting Neurological Recovery in Cardiac Arrest Survivors.Reviews in cardiovascular medicine · 2023Article
- Protocolized Post-Cardiac Arrest Care with Targeted Temperature Management.Acta Cardiologica Sinica · 2022Review
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe gray-white-matter ratio (GWR) measured on brain computed tomography (CT) following return of spontaneous circulation (ROSC) has been reported to be helpful in the prognostication of mortality or comatose status of cardiac arrest victims. However, whether the use of GWR in predicting the outcomes in out-of-hospital cardiac arrest (OHCA) survivors in Taiwan population remains uninvestigated.
methodsThis retrospective observational study conducted in a single tertiary medical center in Taiwan enrolled all the non-traumatic OHCA adults (> 18 years old) with sustained ROSC (≥ 20 minutes) during the period from 2006 to 2014. Patients with following exclusion criteria were further excluded: no brain CT within 24 hours following ROSC; the presence of intracranial hemorrhage, severe old insult, brain tumor, ventriculoperitoneal shunt, and severe image artifact. The GWR values were obtained from the density measurement of bilateral putamen, caudate nuclei, posterior limbs of internal capsule, corpus callosum, medial cortex and medial white matter of cerebrum in Hounsfield unit with region of interest of 0.11 cm
resultsA total of 228 patients were included in the final analysis with 59.2% in male gender and mean age of 65.8-year-old. There were 106 patients (46.5%) survived to hospital discharge and 40 patients (17.5%) discharged with good neurological outcomes. The GWR values of patients who survived to hospital discharge was significantly higher than ones of those who failed (e.g. basal ganglion: 1.239 vs. 1.199,
conclusionThe use of GWR measured on bran CT within 24 hours following ROSC can help in predicting survival-to-hospital discharge and neurological outcome in OHCA survivors.
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Registered trials
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