Evidence map›Paper›PMID 32995141›Full record

ArticlePreventive medicine reports2020

Modeling dynamics of fatal opioid overdose by state and across time.

R Lyle Cooper, Janese Thompson, Ryan Edgerton, Julia Watson, Samuel A MacMaster, Medhat Kalliny, Miranda M Huffman, Paul Juarez, Patricia Mathews-Juarez, Mohammad Tabatabai and 1 more

Abstract read
In one paragraph

Article in Preventive medicine reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. RREACT: A mobile multidisciplinary response to overdose.Journal of community safety & well-being · 2024
    Article
  8. Article
  9. Observational
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

R Lyle CooperDepartment of Family and Community Medicine, Meharry Medical College, 1005 Dr. D.B. Todd Jr. Blvd Nashville, TN 37208, United States.
Janese ThompsonMeharry Medical College, Meharry Medical College, 1005 Dr. D.B. Todd Jr. Blvd, Nashville, TN 37208, United States.
Ryan EdgertonDepartment of Family and Community Medicine, Meharry Medical College, 1005 Dr. D.B. Todd Jr. Blvd Nashville, TN 37208, United States.
Julia WatsonDepartment of Family and Community Medicine, Meharry Medical College, 1005 Dr. D.B. Todd Jr. Blvd Nashville, TN 37208, United States.
Samuel A MacMasterDepartment of Family and Community Medicine at Baylor College of Medicine in Houston, Texas, United States.
Medhat KallinyMeharry Medical College, 1005 Dr. D.B. Todd Jr. Blvd Nashville, TN 37208, United States.
Miranda M HuffmanMeharry Medical College, Meharry Medical College, 1005 Dr. D.B. Todd Jr. Blvd, Nashville, TN 37208, United States.
Paul JuarezDepartment of Family and Community Medicine, Meharry Medical College, 1005 Dr. D.B. Todd Jr. Blvd Nashville, TN 37208, United States.
Patricia Mathews-JuarezDepartment of Family and Community Medicine, Meharry Medical College, 1005 Dr. D.B. Todd Jr. Blvd Nashville, TN 37208, United States.
Mohammad TabatabaiSchool of Graduate Studies and Research, Meharry Medical College 1005 Dr. D.B. Todd Jr. Blvd Nashville, TN 37208, United States.
Karan P SinghDepartment of Epidemiology and Biostatistics, School of Community and Rural Health, The University of Texas Health Science Center at Tyler, Tyler, TX 75708, United States.

Funding

The RCMI Program in Health Disparities Research at Meharry Medical College - SupplementU54MD007586 · NIMHD · MEHARRY MEDICAL COLLEGE · PI Maureen Sanderson · 2017 to 2026
$48.2M
Meharry RCMI Program in Women's Health ResearchG12MD007586 · NIMHD · MEHARRY MEDICAL COLLEGE · PI HILDRETH, JAMES E · 2012 to 2016
$7.8M
NIMHD NIH HHS G12 MD007586NIMHD NIH HHS U54 MD007586
6 · The paper itself

Abstract

Opioid overdose fatalities include deaths from natural opioids (morphine and codeine), semi-synthetic opioids (oxycodone, hydrocodone), synthetic opioids (prescription and illicit fentanyl, tramadol), methadone, and heroin. From 1999 to 2017, there were 702,568 drug overdose deaths in the U.S., with 399,230 attributed to opioids. This study aimed to assess the dynamics of opioid related fatalities throughout the U.S. from 2006-2016. This study is a secondary analysis of data obtained through the Kaiser Family Foundation's analysis of Centers for Disease Control and Prevention data, 1999-2016. The data obtained were from all 50 states and the District of Columbia. A total of 272,130 individuals were included in the analysis. This represents the number of opioid overdose deaths in the United States from 2006-2016. Descriptive analysis of overall rates was conducted and mapped for visualization. Novel predictive models of increase for each drug overdose category were developed and used to calculate rate changes. Finally, the elasticity of change in rate for each drug category was calculated annually for the past 11 years. The highest rate of opioid overdose-related death occurred in West Virginia (40.03 per 100,000). In our secondary analysis, we explored the change in the rate of opioid-related deaths from 2015 to 2016. The changing dynamics of fatal opioid overdose at the state level is critical to guiding policy makers in addressing this crisis. Rates of fatal opioid overdose vary across the states, but we identify some trends. Regional differences are identified in states with the highest overdose rates from all opioids combined.

Indexed as

FatalitiesFentanylHeroinOpiatesOpioidsOverdose

Identifiers

PMID32995141
PMCPMC7516293

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.