Evidence map›Paper›PMID 32995130›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2020

Efficient Isolation and Enrichment of Mesenchymal Stem Cells from Human Embryonic Stem Cells by Utilizing the Interaction between Integrin

Byung-Hyun Cha, Jin-Su Kim, Alvin Bello, Geun-Hui Lee, Do-Hyun Kim, Byoung Ju Kim, Yoshie Arai, Bogyu Choi, Hansoo Park, Soo-Hong Lee

Open access · goldAbstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
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  9. TiOFrontiers in bioengineering and biotechnology · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Byung-Hyun ChaDivision of Cardio-Thoracic Surgery Department of Surgery College of Medicine University of Arizona Tucson AZ 85724 USA.
Jin-Su KimCellenGene R&D Center Open Innovation Building Seoul 02455 Republic of Korea.
Alvin BelloDepartment of Integrative Engineering Chung-Ang University Seoul 06974 Republic of Korea.
Geun-Hui LeeDepartment of Biomedical Science CHA University CHA Biocomplex Seongnam-si Gyeonggi-do 13488 Republic of Korea.ORCID https://orcid.org/0000-0001-6369-8301
Do-Hyun KimDepartment of Medical Biotechnology Dongguk University 32 Dongguk-ro, Ilsandong-gu Goyang Gyeonggi 10326 Republic of Korea.
Byoung Ju KimDepartment of Medical Biotechnology Dongguk University 32 Dongguk-ro, Ilsandong-gu Goyang Gyeonggi 10326 Republic of Korea.
Yoshie AraiDepartment of Medical Biotechnology Dongguk University 32 Dongguk-ro, Ilsandong-gu Goyang Gyeonggi 10326 Republic of Korea.
Bogyu ChoiDepartment of Biomedical Science CHA University CHA Biocomplex Seongnam-si Gyeonggi-do 13488 Republic of Korea.
Hansoo ParkDepartment of Integrative Engineering Chung-Ang University Seoul 06974 Republic of Korea.
Soo-Hong LeeDepartment of Medical Biotechnology Dongguk University 32 Dongguk-ro, Ilsandong-gu Goyang Gyeonggi 10326 Republic of Korea.
Dongguk University · KRCHA University · KRChung-Ang University · KRKorea National Open University · KRUniversity of Arizona · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human pluripotent stem cells (hPSCs) are a potent source of clinically relevant mesenchymal stem cells (MSCs) that confer functional and structural benefits in cell therapy and tissue regeneration. Obtaining sufficient numbers of MSCs in a short period of time and enhancing the differentiation potential of MSCs can be offered the potential to improve the regenerative activity of MSCs therapy. In addition, the underlying processes in the isolation and derivation of MSCs from hPSCs are still poorly understood and controlled. To overcome these clinical needs, an efficient and simplified technique on the isolation of MSCs from spontaneously differentiated human embryonic stem cells (hESCs) via integrin

Indexed as

fibronectinhuman embryonic stem cellsintegrinmesenchymal stem cellsstem cell therapeutics

Identifiers

PMID32995130
PMCPMC7507081
OpenAlexW3043604861

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.