Evidence map›Paper›PMID 32995113›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2020

MT1-MMP-Activated Liposomes to Improve Tumor Blood Perfusion and Drug Delivery for Enhanced Pancreatic Cancer Therapy.

Yan Wei, Sha Song, Nianxiu Duan, Feng Wang, Yuxi Wang, Yiwei Yang, Chengyuan Peng, Junjun Li, Di Nie, Xinxin Zhang and 4 more

Open access · goldAbstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 61 citations in OpenAlex.

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  20. Membrane-enclosedApplied and environmental microbiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Yan WeiShanghai Institute of Materia Medica Chinese Academy of Sciences Shanghai 201203 China.
Sha SongDepartment of Pharmacy Medical College of Nanchang University Nanchang 330066 China.
Nianxiu DuanDepartment of Pharmacy Medical College of Nanchang University Nanchang 330066 China.
Feng WangDepartment of Medicinal Chemistry Shanghai Hansoh Biomedical R&D Inc. Shanghai 201203 China.
Yuxi WangShanghai Institute of Materia Medica Chinese Academy of Sciences Shanghai 201203 China.
Yiwei YangShanghai Institute of Materia Medica Chinese Academy of Sciences Shanghai 201203 China.
Chengyuan PengState Key Laboratory of Drug Research Shanghai Institute of Materia Medica Chinese Academy of Sciences Shanghai 201203 China.
Junjun LiShanghai Institute of Materia Medica Chinese Academy of Sciences Shanghai 201203 China.
Di NieShanghai Institute of Materia Medica Chinese Academy of Sciences Shanghai 201203 China.
Xinxin ZhangShanghai Institute of Materia Medica Chinese Academy of Sciences Shanghai 201203 China.
Shiyan GuoShanghai Institute of Materia Medica Chinese Academy of Sciences Shanghai 201203 China.
Chunliu ZhuShanghai Institute of Materia Medica Chinese Academy of Sciences Shanghai 201203 China.
Miaorong YuShanghai Institute of Materia Medica Chinese Academy of Sciences Shanghai 201203 China.
Yong GanShanghai Institute of Materia Medica Chinese Academy of Sciences Shanghai 201203 China.ORCID https://orcid.org/0000-0002-4579-994X
Chinese Academy of Sciences · CNNanchang University · CNHansoh Pharma (China) · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Promoting tumor angiogenesis effectively and specifically to resolve tumor-associated hypoperfusion holds promise for improving pancreatic cancer therapy. Herein, a doxorubicin (DOX) loaded smart liposome, MC-T-DOX, is constructed, that carries appropriately low-density cilengitide, an

Indexed as

membrane type 1‐matrix metalloproteinase‐activated cilengitidepancreatic cancersmart liposomesvascular promotion

Identifiers

PMID32995113
PMCPMC7507343
OpenAlexW3041026308

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.