Evidence map›Paper›PMID 32995075›Full record

ArticlePeerJ2020

Extracellular vesicles in patients in the acute phase of psychosis and after clinical improvement: an explorative study.

Mette Elise Tunset, Hanne Haslene-Hox, Tim Van Den Bossche, Arne Einar Vaaler, Einar Sulheim, Daniel Kondziella

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PeerJ, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Article
  6. Advances and Utility of the Human Plasma Proteome.Journal of proteome research · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Mette Elise TunsetDepartment of Østmarka- Division of Mental Healthcare, St. Olavs University Hospital, Trondheim, Norway.
Hanne Haslene-HoxDepartment of Biotechnology and Nanomedicine, SINTEF, Trondheim, Norway.
Tim Van Den BosscheVIB - UGent Center for Medical Biotechnology, VIB, Ghent, Belgium.
Arne Einar VaalerDepartment of Østmarka- Division of Mental Healthcare, St. Olavs University Hospital, Trondheim, Norway.
Einar SulheimDepartment of Biotechnology and Nanomedicine, SINTEF, Trondheim, Norway.
Daniel KondziellaDepartment of Neurology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
Norwegian University of Science and Technology · NOSINTEF · NOGhent University · BEUniversity of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extracellular vesicles (EVs) are cell-derived structures that transport proteins, lipids and nucleic acids between cells, thereby affecting the phenotype of the recipient cell. As the content of EVs reflects the status of the originating cell, EVs can have potential as biomarkers. Identifying EVs, including their cells of origin and their cargo, may provide insights in the pathophysiology of psychosis. Here, we present an in-depth analysis and proteomics of EVs from peripheral blood in patients (

Indexed as

Blood brain barrierBrain enriched proteinsExtracellular vesiclesGene ontologyGlutamatergic synapsesGlymphaticsImmune systemProteomicsPsychosisSubstance abuse

Identifiers

PMID32995075
PMCPMC7501784
OpenAlexW3080687429

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.