Evidence map›Paper›PMID 32995038›Full record

ArticleGlobal health, epidemiology and genomics2020

The Sri Lankan twin registry biobank: South Asia's first twin biobank.

Kaushalya Jayaweera, Lakshan Warnakula, Lasith Dissanayake, Anushka Adikari, Sisira Siribaddana, Helena M S Zavos, Fruhling Rijsdijk, Patricia A Zunszain, Carmine M Pariante, Nick Glozier and 2 more

Abstract readTwin Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Global health, epidemiology and genomics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Kaushalya JayaweeraInstitute for Research and Development in Health and Social Care, Colombo, Sri Lanka.ORCID 0000-0003-3780-0901
Lakshan WarnakulaInstitute for Research and Development in Health and Social Care, Colombo, Sri Lanka.
Lasith DissanayakeInstitute for Research and Development in Health and Social Care, Colombo, Sri Lanka.
Anushka AdikariInstitute for Research and Development in Health and Social Care, Colombo, Sri Lanka.
Sisira SiribaddanaDepartment of Medicine, University of Rajarata, Mihintale, Sri Lanka.
Helena M S ZavosDepartment of Psychology, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
Fruhling RijsdijkSocial Genetic and Developmental Research Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
Patricia A ZunszainStress, Psychiatry and Immunology Laboratory, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
Carmine M ParianteStress, Psychiatry and Immunology Laboratory, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
Nick GlozierBrain and Mind Centre, University of Sydney, Sydney, Australia.
Matthew HotopfDepartment of Psychological Medicine, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, UK.
Athula SumathipalaInstitute for Research and Development in Health and Social Care, Colombo, Sri Lanka.

Funding

Medical Research Council G108/603Medical Research Council MR/N029488/1Wellcome Trust 093206/Z/10/Z
6 · The paper itself

Abstract

Introduction: Biobanks are a valuable resource for creating advancements in science through cutting-edge omics research. Twin research methods allow us to understand the degree to which genetics and environmental factors contribute to health outcomes. Methods: The Sri Lankan Twin Registry biobank (SLTR-b) was established in 2015 as part of Colombo Twin and Singleton Follow-up Study. Venous blood and urine were collected from twins and comparative sample of singletons for clinical investigations and biobanking. Results: The SLTR-b currently houses 3369 DNA and serum samples. Biobank specimens are linked to longitudinal questionnaire data, clinical investigations, anthropometric measurements, and other data. Discussion: The SLTR-b aims to address gaps in health and genetics research. It will provide opportunities for academic collaborations, local and international, and capacity building of future research leaders in twin and omics research. This paper provides a cohort profile of the SLTR-b and its linked data, and an overview of the strategies used for biobanking.

Indexed as

Biological Specimen BanksRegistriesTwinsAdultAgedAged, 80 and overAnthropometryAsiaCohort StudiesDNAFemaleHumansMaleMiddle AgedSri LankaSurveys and QuestionnairesDNABiobankDNApopulation basedserumSri Lankatwin research

Identifiers

PMID32995038
PMCPMC7503183

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.