ArticleFood science & nutrition2020
Optimization of ultrasound-assisted solvent extraction of hemp (
Article in Food science & nutrition, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 58 citations in OpenAlex.
- Ultrasound-Ethanol Pretreatment-Assisted Enzymatic Method: A Potential Method to Improve the Quality and Yield ofMolecules (Basel, Switzerland) · 2026Article
- Process optimization for the extraction ofFood chemistry: X · 2025Article
- Optimization, Kinetics, and Thermodynamics of Ultrasound-Assisted Extraction of Phytochemicals from Hemp.ACS omega · 2025Article
- Advancing sustainable food preservation: Ultrasound and thermosonication as novel approaches to enhance nutritional and bioactive properties of broccoli juice.Food chemistry: X · 2025Article
- Correlation between Chemical Fertilization Practices, Phytochemical Response, and Biological Activities ofCombinatorial chemistry & high throughput screening · 2025Review
- Effect of Filtration Process on Oxidative Stability and Minor Compounds of the Cold-Pressed Hempseed Oil during Storage.Antioxidants (Basel, Switzerland) · 2023Article
- Modelling and optimisation of ultrasound-assisted extraction of roselle phenolic compounds using the surface response method.Scientific reports · 2023Article
- Ultrasound-Assisted Alcoholic Extraction of Lesser Mealworm Larvae Oil: Process Optimization, Physicochemical Characteristics, and Energy Consumption.Antioxidants (Basel, Switzerland) · 2022Article
- Impact of ultrasonication applications on color profile of foods.Ultrasonics sonochemistry · 2022Review
- Postharvest Operations of Cannabis and Their Effect on Cannabinoid Content: A Review.Bioengineering (Basel, Switzerland) · 2022Review
- Evaluation of thermo-chemical conversion temperatures of cannabinoid acids in hemp (Cannabis sativa L.) biomass by pressurized liquid extraction.Journal of cannabis research · 2021Article
- Antioxidant Activity of Hemp (Antioxidants (Basel, Switzerland) · 2021Article
- Optimization of ultrasound-assisted solvent extraction of hemp (Food science & nutrition · 2020Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this study, the effect of solvent ratio of hexane to isopropanol (0:100, 50:50, and 100:0 v/v%), extraction temperature (30, 45, and 60°C), and time (30, 60, and 90 min) were investigated on the oil extraction efficiency, total phenol content, DPPH radical scavenging, peroxide value, and oil color index. Extraction conditions were optimized by response surface methodology and Box-Behnken design. The optimal conditions were obtained as hexane-to-isopropanol ratio of approximately 3:2, temperature of 40.26°C, and ultrasonication time of 54.40 min. Then, the hemp seed oil was extracted under the optimal conditions. The optimal predicted contents for oil yield (31.22%), total phenolics (3.19 mg GA/g oil), DPPH inhibition (73.86%), peroxide (4.62 meq/kg), and color index (28.2) were agreed with the predicted conditions because the RSE values were less than 5%. Hemp seed oil can be used extensively due to its high nutritional values, and antioxidant potential and ultrasound can improve oil extraction as a simple and fast method.
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