Evidence map›Paper›PMID 32994835›Full record

ArticleRadiology case reports2020

CT-guided biopsy in the differential diagnosis of Sjogren syndrome associated cystic lung disease: A case of lung nodular AL-

Claudio Tirelli, Giovanni Zanframundo, Adele Valentini, Chandra Bortolotto, Roberto Dore, Tiberio Oggionni, Paolo Milani, Elena Bravi, Zamir Kadija, Francesca Mariani and 5 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Radiology case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 1 country.

Claudio TirelliDepartment of Internal Medicine and Therapeutics, Division of Respiratory Diseases, University of Pavia and IRCCS Policlinico San Matteo Foundation, Pavia, Italy.
Giovanni ZanframundoDivision of Rheumatology, University and IRCCS Policlinico S. Matteo Foundation, Pavia, Italy.
Adele ValentiniDivision of Radiology, IRCCS Policlinico S. Matteo Foundation, Pavia, Italy.
Chandra BortolottoDivision of Radiology, IRCCS Policlinico S. Matteo Foundation, Pavia, Italy.
Roberto DoreRadiology Unit, Istituti Clinici Città di Pavia, Pavia, Italy.
Tiberio OggionniDivision of Respiratory Diseases, IRCCS Policlinico San Matteo Foundation, Pavia, Italy.
Paolo MilaniDepartment of Molecular Medicine, Amyloidosis Research and Treatment Center, Foundation "Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Policlinico San Matteo", University of Pavia, Pavia, Italy.
Elena BraviUnit of Rheumatology, Guglielmo da Saliceto Hospital, Piacenza, Italy.
Zamir KadijaDivision of Internal Medicine, Azienda Sanitaria dell'Alto Adige, Brunico Hospital, Brunico, Italy.
Francesca MarianiDivision of Respiratory Diseases, IRCCS Policlinico San Matteo Foundation, Pavia, Italy.
Veronica CodulloDivision of Rheumatology, University and IRCCS Policlinico S. Matteo Foundation, Pavia, Italy.
Patrizia MorbiniPathology Unit, University and IRCCS Policlinico S. Matteo Foundation, Pavia, Italy.
Giovanni PalladiniDepartment of Molecular Medicine, Amyloidosis Research and Treatment Center, Foundation "Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Policlinico San Matteo", University of Pavia, Pavia, Italy.
Federica MeloniDepartment of Internal Medicine and Therapeutics, Division of Respiratory Diseases, University of Pavia and IRCCS Policlinico San Matteo Foundation, Pavia, Italy.
Lorenzo CavagnaDivision of Rheumatology, University and IRCCS Policlinico S. Matteo Foundation, Pavia, Italy.
Istituti di Ricovero e Cura a Carattere Scientifico · ITUniversity of Pavia · ITGuglielmo da Saliceto Hospital · ITIstituti Clinici Scientifici Maugeri · ITPoliclinico San Matteo Fondazione · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulmonary involvement in Sjogren syndrome (SS) could manifest as cystic lung disease (CLD). CLD in SS includes lymphocytic interstitial pneumonia (LIP) and pulmonary amyloidosis. Differential diagnosis usually requires surgical lung biopsy, whereas CT-guided percutaneous fine needle aspiration biopsy (CT-FNAB) has not yet explored. We describe the case of a 63-year-old never smoker Caucasian female with a SS diagnosis who displayed a newly detected diffuse CLD at high-resolution computed tomography, though totally asymptomatic. Given the favorable location of one big lesion at the superior left lobe, a CT-FNAB was proposed instead of a more invasive SLB. At histology examination a diagnosis of pulmonary nodular AL kappa amyloidosis in the context of SS was established. In conclusion, CT-FNAB might represent an alternative and less invasive diagnostic procedure than SLB in the differential diagnosis of CLD, even if further research is needed. Moreover, this case presents an unusual association between SS and pulmonary nodular AL kappa amyloidosis, with pulmonary nodules and cysts without systemic manifestations.

Indexed as

AmyloidosisCT guided fine needle aspiration biopsyCystic lung diseaseSjogren syndrome

Identifiers

PMID32994835
PMCPMC7501412
OpenAlexW3085228807

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.