ArticleSaudi journal of biological sciences2020
Influence of polymerization method on the cytotoxicity of three different denture base acrylic resins polymerized in different methods.
Article in Saudi journal of biological sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 18 citations in OpenAlex.
- Article
- In Vitro Mechanical Evaluation of Prosthodontic Dental Acrylics Fabricated by Conventional and Additive Techniques.Materials (Basel, Switzerland) · 2026Article
- Advancing Drug Delivery with Biodegradable Molecularly Imprinted Polymers: From Design to Clinical Prospects.Drug design, development and therapy · 2026Review
- Comparison of bond strength for light-cure tray to addition silicone impression material after three surface treatments: AnBioinformation · 2025Article
- Water temperature for fabrication of autopolymerizing polymethyl methacrylate (PMMA) interim fixed restoration affects cytotoxicity and residual methyl methacrylate (MMA).Journal of dental sciences · 2024Article
- Obturator Manufacturing for Oronasal Fistula after Cleft Palate Repair: A Review from Handicraft to the Application of Digital Techniques.Journal of functional biomaterials · 2022Review
- Article
- Review
- [Effect of mouthwash with cetylpyridine chloride on the surface microhardness of self-curing, heat-curing and CAD CAM polymethyl methacrylate. In vitro study].Revista cientifica odontologica (Universidad Cientifica del Sur)Article
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
statement of problemAcrylic plastics are used for over 80 years for the manufacture of prostheses. This kind of material has some limitations, one of them is a residual monomer, that remains after the polymerization has been terminated, which can influence the biological properties of the final medical device. THE PURPOSE: The aim of this investigations was a comparison of the residual monomer concentration and cytotoxic effect of three various acrylic materials which differ in the polymerization method (hot-cured, polymerized under pressure and at lower temperatures). MATERIAL AND
methodsThe cytotoxicity of three different acrylic resins from the same producer were tested on the in vitro model (VERO CCL-81) by MTT assay. The residual monomer of acrylic materials was detected by gas chromatography.
resultsThe Superacryl Plus material polymerized in hot water has a residual monomer concentration of 0.67 ± 0.05%, Superpont C + B hardened under pressure of 2.61 ± 0.208%, and Premacryl Plus after cold curing process has 3.53 ± 0.27% of uncured MMA. The results revealed that the least cytotoxic effect were observed in case of a thermally polymerized material.
conclusionMaterial polymerized in high temperatures has lower residual monomer concentration and not affect cell cultures. Self-curing materials polymerized in lower temperature have a higher concentration of residual monomer, which reduces the number of living cells by 20%, which can cause allergic reaction shortly after new denture was prepared.
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