ArticleNature methods2020
EthoLoop: automated closed-loop neuroethology in naturalistic environments.
Article in Nature methods, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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Who cites it
38 citing papers in PubMed, 126 citations in OpenAlex.
- Wireless neural recordings from groups of mice inside and outside the laboratory.Nature methods · 2026Article
- A wireless modular platform for neuro-behavioral recording and closed-loop manipulation in small animals.Nature methods · 2026Article
- Experience-dependent emergence of multi-scale spatial organization during foraging in freely moving marmosets.iScience · 2026Article
- EthoPy provides an accessible platform for reproducible behavioral neuroscience.Cell reports methods · 2026Article
- Primate neuroethology: a new synthesis.Trends in cognitive sciences · 2026Review
- Neural Bases of Collective Social Behavior and Group Interactions across Species.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Review
- Foraging as an ethological framework for neuroscience.Trends in neurosciences · 2025Review
- Mouse lemurs.Nature methods · 2025Article
- DISSeCT: An unsupervised framework for high-resolution mapping of rodent behavior using inertial sensors.PLoS biology · 2025Article
- RpiBeh offers a versatile open source solution for rodent behavior tracking and closed loop interventions.Scientific reports · 2025Article
- Real-Time Behaviour Recognition on Bio-Loggers Enables Autonomous Audio Playback Experiments in Free-Ranging Seabirds.Ecology and evolution · 2025Article
- The impact of machine learning on ethological neuroscience.Frontiers in behavioral neuroscience · 2025Review
- ONIX: a unified open-source platform for multimodal neural recording and perturbation during naturalistic behavior.Nature methods · 2025Article
- eLemur: A cellular-resolution 3D atlas of the mouse lemur brain.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- A-SOiD, an active-learning platform for expert-guided, data-efficient discovery of behavior.Nature methods · 2024Article
- A perspective on neuroethology: what the past teaches us about the future of neuroethology.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2024Review
- ReptiLearn: An automated home cage system for behavioral experiments in reptiles without human intervention.PLoS biology · 2024Article
- SARTAB, a scalable system for automated real-time behavior detection based on animal tracking and Region Of Interest analysis: validation on fish courtship behavior.Frontiers in behavioral neuroscience · 2024Article
- A unified open-source platform for multimodal neural recording and perturbation during naturalistic behavior.bioRxiv : the preprint server for biology · 2023Article
- SMART-BARN: Scalable multimodal arena for real-time tracking behavior of animals in large numbers.Science advances · 2023Article
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Accurate tracking and analysis of animal behavior is crucial for modern systems neuroscience. However, following freely moving animals in naturalistic, three-dimensional (3D) or nocturnal environments remains a major challenge. Here, we present EthoLoop, a framework for studying the neuroethology of freely roaming animals. Combining real-time optical tracking and behavioral analysis with remote-controlled stimulus-reward boxes, this system allows direct interactions with animals in their habitat. EthoLoop continuously provides close-up views of the tracked individuals and thus allows high-resolution behavioral analysis using deep-learning methods. The behaviors detected on the fly can be automatically reinforced either by classical conditioning or by optogenetic stimulation via wirelessly controlled portable devices. Finally, by combining 3D tracking with wireless neurophysiology we demonstrate the existence of place-cell-like activity in the hippocampus of freely moving primates. Taken together, we show that the EthoLoop framework enables interactive, well-controlled and reproducible neuroethological studies in large-field naturalistic settings.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.