Evidence map›Paper›PMID 32994477›Full record

ArticleScientific reports2020

Decrease of T-cells exhaustion markers programmed cell death-1 and T-cell immunoglobulin and mucin domain-containing protein 3 and plasma IL-10 levels after successful treatment of chronic hepatitis C.

Sylwia Osuch, Tomasz Laskus, Hanna Berak, Karol Perlejewski, Karin J Metzner, Marcin Paciorek, Marek Radkowski, Kamila Caraballo Cortés

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Double Positive CD4Cells · 2023
    Article
  10. High CD8Frontiers in immunology · 2023
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Distinct Immune Profiles of Exhausted Effector and Memory CD8Frontiers in cellular and infection microbiology · 2021
    Observational
  18. Current Approaches for Glioma Gene Therapy and Virotherapy.Frontiers in molecular neuroscience · 2021
    Review
  19. Splenic CD4International journal of immunopathology and pharmacology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Sylwia OsuchDepartment of Immunopathology of Infectious and Parasitic Diseases, Medical University of Warsaw, 3c Pawińskiego Street, 02-106, Warsaw, Poland.
Tomasz LaskusDepartment of Adult Infectious Diseases, Medical University of Warsaw, Warsaw, Poland.
Hanna BerakOutpatient Clinic, Warsaw Hospital for Infectious Diseases, Warsaw, Poland.
Karol PerlejewskiDepartment of Immunopathology of Infectious and Parasitic Diseases, Medical University of Warsaw, 3c Pawińskiego Street, 02-106, Warsaw, Poland.
Karin J MetznerDivision of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Marcin PaciorekDepartment of Adult Infectious Diseases, Medical University of Warsaw, Warsaw, Poland.
Marek RadkowskiDepartment of Immunopathology of Infectious and Parasitic Diseases, Medical University of Warsaw, 3c Pawińskiego Street, 02-106, Warsaw, Poland.
Kamila Caraballo CortésDepartment of Immunopathology of Infectious and Parasitic Diseases, Medical University of Warsaw, 3c Pawińskiego Street, 02-106, Warsaw, Poland. kcaraballo@wum.edu.pl.
Medical University of Warsaw · PLUniversity of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During chronic hepatitis C virus (HCV) infection, both CD4

Indexed as

AdultAntiviral AgentsApoptosisBiomarkers, PharmacologicalCD3 ComplexCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesFemaleFlow CytometryHepatitis A Virus Cellular Receptor 2Hepatitis C, ChronicHumansInterleukin-10Liver CirrhosisMaleMiddle AgedAntiviral AgentsBiomarkers, PharmacologicalCD3 ComplexHAVCR2 protein, humanHepatitis A Virus Cellular Receptor 2IL10 protein, humanInterleukin-10Mucin-3Programmed Cell Death 1 Receptor

Identifiers

PMID32994477
PMCPMC7524731
OpenAlexW3091227297

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.