Evidence map›Paper›PMID 32994334›Full record

ArticlemBio2020

Beyond Toxin Transport: Novel Role of ABC Transporter for Enzymatic Machinery of Cereulide NRPS Assembly Line.

A Gacek-Matthews, Z Chromiková, M Sulyok, G Lücking, I Barák, M Ehling-Schulz

Open access · goldAbstract read
In one paragraph

Article in mBio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Cereulide and EmeticFoods (Basel, Switzerland) · 2023
    Review
  10. Article
  11. Molecules (Basel, Switzerland) · 2022
    Article
  12. Article
  13. Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

A Gacek-MatthewsInstitute of Microbiology, Vetmeduni Vienna, Vienna, Austria.ORCID 0000-0001-5884-583X
Z ChromikováInstitute of Microbiology, Vetmeduni Vienna, Vienna, Austria.
M SulyokInstitute for Bioanalytics and Agro-Metabolomics, Department IFA-Tulln, University of Natural Resources and Life Sciences Vienna (BOKU), Vienna, Austria.
G LückingZIEL Institute for Food and Health, Technische Universität München, Freising, Germany.
I BarákInstitute of Molecular Biology, Slovak Academy of Sciences, Bratislava, Slovakia imrich.barak@savba.sk monika.ehling-schulz@vetmeduni.ac.at.
M Ehling-SchulzInstitute of Microbiology, Vetmeduni Vienna, Vienna, Austria imrich.barak@savba.sk monika.ehling-schulz@vetmeduni.ac.at.ORCID 0000-0001-7384-0594
Slovak Academy of Sciences · SKBOKU University · ATLeibniz-Institute for Food Systems Biology at the Technical University of Munich · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nonribosomal peptide synthetases (NRPSs) and polyketide synthetases (PKSs) play a pivotal role in the production of bioactive natural products, such as antibiotics and cytotoxins. Despite biomedical and pharmaceutical importance, the molecular mechanisms and architectures of these multimodular enzyme complexes are not fully understood. Here, we report on an ABC transporter that forms a vital part of the nonribosomal peptide biosynthetic machinery. Emetic

Indexed as

Peptide Biosynthesis, Nucleic Acid-IndependentATP-Binding Cassette TransportersBacillus cereusDepsipeptidesGenes, BacterialMultigene FamilyPeptide SynthasesSecondary MetabolismATP-Binding Cassette TransporterscereulideDepsipeptidesnon-ribosomal peptide synthasePeptide SynthasesABC transporterBacillus cereusbacterial adenylate cyclase-based two-hybrid system (BACTH)cereulidenonribosomal peptide synthetases (NRPS)

Identifiers

PMID32994334
PMCPMC7527721
OpenAlexW3091563984

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.