ArticlemSystems2020
Size Shapes the Active Microbiome of Methanogenic Granules, Corroborating a Biofilm Life Cycle.
Article in mSystems, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 23 citations in OpenAlex.
- Size matters: Anaerobic granules exhibit distinct ecological and physico-chemical gradients across biofilm size.Environmental science and ecotechnology · 2025Article
- Bioenergetically constrained dynamical microbial interactions govern the performance and stability of methane-producing bioreactors.NPJ biofilms and microbiomes · 2025Article
- Individual methanogenic granules are whole-ecosystem replicates with reproducible responses to environmental cues.Environmental microbiome · 2024Article
- First evidence for temperature's influence on the enrichment, assembly, and activity of polyhydroxyalkanoate-synthesizing mixed microbial communities.Frontiers in systems biology · 2024Article
- Unifying concepts in methanogenic, aerobic, and anammox sludge granulation.Environmental science and ecotechnology · 2024Review
- Quantification of depth-dependent microbial growth in encapsulated systems.Microbial biotechnology · 2023Article
- Effects of phenyl acids on different degradation phases during thermophilic anaerobic digestion.Frontiers in microbiology · 2023Article
- Beyond Basic Diversity Estimates-Analytical Tools for Mechanistic Interpretations of Amplicon Sequencing Data.Microorganisms · 2022Review
- Metabolically Active Prokaryotes and Actively Transcribed Antibiotic Resistance Genes in Sewer Systems: Implications for Public Health and Microbially Induced Corrosion.Microbial ecology · 2022Article
- A droplet-based microfluidic approach to isolating functional bacteria from gut microbiota.Frontiers in cellular and infection microbiology · 2022Article
- Methanotrophs: Discoveries, Environmental Relevance, and a Perspective on Current and Future Applications.Frontiers in microbiology · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
Methanogenic archaea are key players in cycling organic matter in nature but also in engineered waste treatment systems, where they generate methane, which can be used as a renewable energy source. In such systems in the built environment, complex methanogenic consortia are known to aggregate into highly organized, spherical granular biofilms comprising the interdependent microbial trophic groups mediating the successive stages of the anaerobic digestion (AD) process. This study separated methanogenic granules into a range of discrete size fractions, hypothesizing different biofilm growth stages, and separately supplied each with specific substrates to stimulate the activity of key AD trophic groups, including syntrophic acid oxidizers and methanogens. Rates of specific methanogenic activity were measured, and amplicon sequencing of 16S rRNA gene transcripts was used to resolve phylotranscriptomes across the series of size fractions. Increased rates of methane production were observed in each of the size fractions when hydrogen was supplied as the substrate compared with those of volatile fatty acids (acetate, propionate, and butyrate). This was connected to a shift toward hydrogenotrophic methanogenesis dominated by
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.