Evidence map›Paper›PMID 32994272›Full record

ArticleDiabetes2020

The KINGS

Amazon L F Austin, Lydia F Daniels Gatward, Miriam Cnop, Gabriel Santos, David Andersson, Sally Sharp, Clive Gentry, Stuart Bevan, Peter M Jones, Aileen J F King

Open access · bronzeAbstract read
In one paragraph

Article in Diabetes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Distinct states of proinsulin misfolding in MIDY.Cellular and molecular life sciences : CMLS · 2021
    Article
  9. Regulation of lipid metabolism by the unfolded protein response.Journal of cellular and molecular medicine · 2021
    Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Amazon L F AustinDepartment of Diabetes, School of Life Course Sciences, King's College London, London, U.K.
Lydia F Daniels GatwardDepartment of Diabetes, School of Life Course Sciences, King's College London, London, U.K.
Miriam CnopULB Center for Diabetes Research, Université Libre de Bruxelles, Brussels, Belgium.
Gabriel SantosDepartment of Diabetes, School of Life Course Sciences, King's College London, London, U.K.ORCID 0000-0002-5112-1692
David AnderssonWolfson Centre for Age-Related Diseases, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, U.K.
Sally SharpWolfson Centre for Age-Related Diseases, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, U.K.ORCID 0000-0001-7451-8548
Clive GentryWolfson Centre for Age-Related Diseases, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, U.K.
Stuart BevanWolfson Centre for Age-Related Diseases, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, U.K.
Peter M JonesDepartment of Diabetes, School of Life Course Sciences, King's College London, London, U.K.
Aileen J F KingDepartment of Diabetes, School of Life Course Sciences, King's College London, London, U.K. aileen.king@kcl.ac.uk.ORCID 0000-0001-5759-7985
King's College London · GBUniversité Libre de Bruxelles · BE

Funding

Medical Research Council
6 · The paper itself

Abstract

Animal models are important tools in diabetes research because ethical and logistical constraints limit access to human tissue. β-Cell dysfunction is a common contributor to the pathogenesis of most types of diabetes. Spontaneous hyperglycemia was developed in a colony of C57BL/6J mice at King's College London (KCL). Sequencing identified a mutation in the

Indexed as

Disease Models, AnimalAnimalsDiabetes MellitusEcosystemEndoplasmic Reticulum StressFemaleGlucose Tolerance TestHumansInsulinInsulin-Secreting CellsMaleMiceMice, Inbred StrainsMutationPolymorphism, Single NucleotideInsulin

Identifiers

PMID32994272
PMCPMC7679781
OpenAlexW3091724034

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.