Evidence map›Paper›PMID 32993814›Full record

ArticleBMC research notes2020

High prevalence of hepatitis A in indigenous population in north Brazil.

Vanessa Salete de Paula, Flavio Augusto Pádua Milagres, Guilherme de Macêdo Oliveira, Juliana Custódio Miguel, Helena Medina Cruz, Leticia de Paula Scalioni, Vanessa Alves Marques, Monica de Avelar Figueiredo Mafra Magalhães, Anselmo Rocha Romão, Renata Gracie and 1 more

Open access · goldAbstract read
In one paragraph

Article in BMC research notes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Vanessa Salete de PaulaMolecular Virology Laboratory, Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro, Brazil.
Flavio Augusto Pádua MilagresFederal University of Tocantins, UFT, Tocantins, Brazil.
Guilherme de Macêdo OliveiraCancer Nacional Institute, INCA, Rio de Janeiro, Brazil.
Juliana Custódio MiguelLaboratory of Viral Hepatitis, Oswaldo Cruz Institute, FIOCRUZ, Helio and Peggy Pereira Pavillion, Ground Floor, Room B09, FIOCRUZ Av. Brasil, 4365 - Manguinhos, Rio de Janeiro, 210360-040, Brazil.
Helena Medina CruzLaboratory of Viral Hepatitis, Oswaldo Cruz Institute, FIOCRUZ, Helio and Peggy Pereira Pavillion, Ground Floor, Room B09, FIOCRUZ Av. Brasil, 4365 - Manguinhos, Rio de Janeiro, 210360-040, Brazil.
Leticia de Paula ScalioniLaboratory of Viral Hepatitis, Oswaldo Cruz Institute, FIOCRUZ, Helio and Peggy Pereira Pavillion, Ground Floor, Room B09, FIOCRUZ Av. Brasil, 4365 - Manguinhos, Rio de Janeiro, 210360-040, Brazil.
Vanessa Alves MarquesLaboratory of Viral Hepatitis, Oswaldo Cruz Institute, FIOCRUZ, Helio and Peggy Pereira Pavillion, Ground Floor, Room B09, FIOCRUZ Av. Brasil, 4365 - Manguinhos, Rio de Janeiro, 210360-040, Brazil.
Monica de Avelar Figueiredo Mafra MagalhãesLaboratory of Information in Health, Institute of Communication and Technological and Scientific Information in Health (ICICT), FIOCRUZ, Rio de Janeiro, Brazil.
Anselmo Rocha RomãoLaboratory of Information in Health, Institute of Communication and Technological and Scientific Information in Health (ICICT), FIOCRUZ, Rio de Janeiro, Brazil.
Renata GracieLaboratory of Information in Health, Institute of Communication and Technological and Scientific Information in Health (ICICT), FIOCRUZ, Rio de Janeiro, Brazil.
Livia Melo VillarLaboratory of Viral Hepatitis, Oswaldo Cruz Institute, FIOCRUZ, Helio and Peggy Pereira Pavillion, Ground Floor, Room B09, FIOCRUZ Av. Brasil, 4365 - Manguinhos, Rio de Janeiro, 210360-040, Brazil. liviafiocruz@gmail.com.ORCID http://orcid.org/0000-0001-7644-8969
Fundação Oswaldo Cruz · BRInstituto Nacional de Câncer - INCA · BRUniversidade Federal do Tocantins · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesLittle is known about hepatitis A virus (HAV) prevalence in indigenous communities. This study aims to evaluate the prevalence of HAV in indigenous community compared to urban population located at Western Amazon in Brazil.

resultsA total of 872 serum samples were obtained from 491 indigenous and 381 non indigenous individuals aging 0 to 90 years. Samples were tested for total and IgM anti-HAV and positive IgM samples were tested for HAV RNA. The overall prevalence of total anti-HAV was 87%, increased according age showing 100% of prevalence in those aging more than 30 years (p < 0.0001) and it was similar among indigenous and urban population. Total anti-HAV prevalence varied between tribes (p < 0.0001) and urban sites (p = 0.0014) and spatial distribution showed high prevalence in homes that received up to 100 dollars. IgM anti-HAV prevalence was 1.7% with predominance in males, those aging more than 41 years. No HAV RNA was detected. In conclusion, high overall anti-HAV prevalence was found in indigenous communities in North Brazil demonstrating the importance of universal vaccination in this group.

Indexed as

Hepatitis AAdultBrazilHepatitis A AntibodiesHumansMalePopulation GroupsPrevalenceSeroepidemiologic StudiesHepatitis A AntibodiesHepatitis AIndigenous populationPrevalenceVaccination

Identifiers

PMID32993814
PMCPMC7526101
OpenAlexW3090112026

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.