Evidence map›Paper›PMID 32993535›Full record

ArticleBMC infectious diseases2020

Hemophagocytic syndrome associated with Mycobacterium bovis in a patient with X-SCID: a case report.

Buyun Shi, Ming Chen, Zhi Xia, Shuna Xiao, Wen Tang, Chenguang Qin, Ying Cheng, Tao Huang, Chengjiao Huang, Yong Li and 1 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.

  1. Pooled it
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  3. HemizygousThe application of clinical genetics · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Buyun ShiDepartment of Pediatric Intensive Care Unit (PICU), Maternal and Child Health Hospital of Hubei Province (Women and Children's Hospital of Hubei Province), NO.745 Wu LuoRoad, Hongshan District, Wuhan City, 430070, Hubei Province, China.
Ming ChenDepartment of Dermatology, Maternal and Child Health Hospital of Hubei Province (Women and Children's Hospital of Hubei Province), NO.745 Wu LuoRoad, Hongshan District, Wuhan City, 430070, Hubei Province, China.
Zhi XiaDepartment of Pediatric Intensive Care Unit (PICU), Maternal and Child Health Hospital of Hubei Province (Women and Children's Hospital of Hubei Province), NO.745 Wu LuoRoad, Hongshan District, Wuhan City, 430070, Hubei Province, China.
Shuna XiaoDepartment of Pediatric Intensive Care Unit (PICU), Maternal and Child Health Hospital of Hubei Province (Women and Children's Hospital of Hubei Province), NO.745 Wu LuoRoad, Hongshan District, Wuhan City, 430070, Hubei Province, China.
Wen TangDepartment of Pediatric Intensive Care Unit (PICU), Maternal and Child Health Hospital of Hubei Province (Women and Children's Hospital of Hubei Province), NO.745 Wu LuoRoad, Hongshan District, Wuhan City, 430070, Hubei Province, China.
Chenguang QinDepartment of Pediatric Intensive Care Unit (PICU), Maternal and Child Health Hospital of Hubei Province (Women and Children's Hospital of Hubei Province), NO.745 Wu LuoRoad, Hongshan District, Wuhan City, 430070, Hubei Province, China.
Ying ChengDepartment of Pediatric Intensive Care Unit (PICU), Maternal and Child Health Hospital of Hubei Province (Women and Children's Hospital of Hubei Province), NO.745 Wu LuoRoad, Hongshan District, Wuhan City, 430070, Hubei Province, China.
Tao HuangDepartment of Pediatric Intensive Care Unit (PICU), Maternal and Child Health Hospital of Hubei Province (Women and Children's Hospital of Hubei Province), NO.745 Wu LuoRoad, Hongshan District, Wuhan City, 430070, Hubei Province, China.
Chengjiao HuangDepartment of Pediatric Intensive Care Unit (PICU), Maternal and Child Health Hospital of Hubei Province (Women and Children's Hospital of Hubei Province), NO.745 Wu LuoRoad, Hongshan District, Wuhan City, 430070, Hubei Province, China.
Yong LiDepartment of Pediatric Intensive Care Unit (PICU), Maternal and Child Health Hospital of Hubei Province (Women and Children's Hospital of Hubei Province), NO.745 Wu LuoRoad, Hongshan District, Wuhan City, 430070, Hubei Province, China.
Hui XuDepartment of Pediatric Intensive Care Unit (PICU), Maternal and Child Health Hospital of Hubei Province (Women and Children's Hospital of Hubei Province), NO.745 Wu LuoRoad, Hongshan District, Wuhan City, 430070, Hubei Province, China. hsliu402@sina.com.ORCID http://orcid.org/0000-0002-7493-5103
Hubei Provincial Women and Children's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMycobacterium bovis could infect patients with immunodeficiency or immunosuppressive conditions via Bacillus Calmette-Guérin (BCG) vaccination. Tuberculosis-related hemophagocytic syndrome (HPS) is reported, but not HPS caused by Mycobacterium bovis in children. CASE PRESENTATION: A 4-month Chinese boy presented fever and cough. The initial laboratory investigation showed the lymphocyte count of 0.97 × 10

conclusionsA boy with X-SCID was diagnosed with M. bovis-associated HPS, emphasizing that X-SCID should be considered when M. bovis is detected in a male infant with low lymphocyte counts.

Indexed as

Antibiotics, AntitubercularHigh-Throughput Nucleotide SequencingHumansInfantInterleukin Receptor Common gamma SubunitIsoniazidLymphohistiocytosis, HemophagocyticMaleMutationMycobacterium bovisMycobacterium tuberculosisPatient DischargePolymerase Chain ReactionPyrazinamideRifampinTreatment OutcomeAntibiotics, AntitubercularIL2RG protein, humanInterleukin Receptor Common gamma SubunitIsoniazidPyrazinamideRifampinHemophagocytic syndromeIL2RGMycobacterium bovisX-SCID

Identifiers

PMID32993535
PMCPMC7525942
OpenAlexW3089731956

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.