ArticleBMC gastroenterology2020
The association between inflammatory potential of diet and disease activity: results from a cross-sectional study in patients with inflammatory bowel disease.
Article in BMC gastroenterology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
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Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Relationship between diet quality and inflammatory bowel disease: a systematic review of observational studies.BMC gastroenterology · 2025Pooled it
- Index-Based Dietary Patterns and Inflammatory Bowel Disease: A Systematic Review of Observational Studies.Advances in nutrition (Bethesda, Md.) · 2021Pooled it
- Dietary inflammatory index and objective disease activity in IBD: no association found.European journal of clinical nutrition · 2026Observational
- Obesity: An Overlooked Factor in Inflammatory Bowel Disease.International journal of molecular sciences · 2026Review
- The Association between Empirical Dietary Inflammatory Pattern and Disease Activity and Quality of Life in Patients with Inflammatory Bowel Disease: A Cross-Sectional Study.International journal of preventive medicine · 2026Article
- Ultra-Processed Food Intake in Children with Inflammatory Bowel Disease: A Pilot Case-Control Study.Nutrients · 2025Article
- Bacteroides uniformis ameliorates pro-inflammatory diet-exacerbated colitis by targeting endoplasmic reticulum stress-mediated ferroptosis.Journal of advanced research · 2025Article
- Association Between Pro-Inflammatory Potential of Diet and Inflammatory Parameters in a Group of Patients with Inflammatory Bowel Disease.Nutrients · 2025Article
- Association between Dietary Inflammatory Index and Ulcerative Colitis: a case-control study.BMC gastroenterology · 2025Article
- Association between dietary inflammatory index and disease activity in patients with ulcerative colitis.Scientific reports · 2024Article
- Knowledge Levels About Inflammatory Bowel Disease Vary Between Healthcare Professional Groups.Digestive diseases and sciences · 2024Article
- Pro-Inflammatory Diet Is Correlated with HighNutrients · 2023Article
- Protective effect and mechanism insight of purified Antarctic kill phospholipids against mice ulcerative colitis combined with bioinformatics.Natural products and bioprospecting · 2023Article
- Efficacy of a Digital Personalized Elimination Diet for the Self-Management of Irritable Bowel Syndrome and Comorbid Irritable Bowel Syndrome and Inflammatory Bowel Disease.Clinical and translational gastroenterology · 2023Article
- Dietary Patterns and Gut Microbiota Changes in Inflammatory Bowel Disease: Current Insights and Future Challenges.Nutrients · 2022Review
- Processed Food as a Risk Factor for the Development and Perpetuation of Crohn's Disease-The ENIGMA Study.Nutrients · 2022Article
- Diet Quality and Dietary Inflammatory Index in Dutch Inflammatory Bowel Disease and Irritable Bowel Syndrome Patients.Nutrients · 2022Article
- Central obesity in school-aged children increases the likelihood of developing paediatric autoimmune diseases.Pediatric obesity · 2022Article
- Association between Dietary Inflammatory Index and Sarcopenia in Crohn's Disease Patients.Nutrients · 2022Article
- Patient experiences with the role of physical activity in inflammatory bowel disease: results from a survey and interviews.BMC gastroenterology · 2021Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
backgroundDiet may play a role in disease status in patients with inflammatory bowel disease. We tested whether the inflammatory potential of diet, based on a summation of pro- and anti-inflammatory nutrients, is associated with disease activity in patients with Crohn's disease and ulcerative colitis.
methodsParticipants completed a disease activity questionnaire (short Crohn's Disease Activity (sCDAI) or Patient Simple Clinical Colitis Activity Index (P-SCCAI)) and a Food Frequency Questionnaire (FFQ). FFQ data were used to calculate the Dietary Inflammatory Index (DII) which enables categorization of individuals' diets according to their inflammatory potential on a continuum from pro- to anti-inflammatory. Associations with disease activity were investigated by multiple linear regression.
resultsThe analysis included 329 participants; 168 with Crohn's disease (median sCDAI score 93 [IQR 47-156]), and 161 with ulcerative colitis (median P-SCCAI score 1 [IQR 1-3]). Mean DII was 0.71 ± 1.33, suggesting a slightly pro-inflammatory diet. In Crohn's disease, the DII was positively associated with disease activity, even after adjustment for confounders (p = 0.008). The mean DII was significantly different between participants in remission and with mild and moderately active disease (0.64, 0.97 and 1.52 respectively, p = 0.027). In ulcerative colitis, the association was not significant.
conclusionsDisease activity was higher in IBD participants with a more pro-inflammatory diet with statistical significance in Crohn's disease. Although the direction of causality is not clear, this association strengthens the role for diet in medical treatment, which should be tested in an intervention study.
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