ArticleBMC plant biology2020
A WRKY transcription factor, TaWRKY42-B, facilitates initiation of leaf senescence by promoting jasmonic acid biosynthesis.
Article in BMC plant biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- Overview of molecular mechanisms of plant leaf development: a systematic review.Frontiers in plant science · 2023Pooled it
- Regulatory Network of Leaf Senescence inInternational journal of molecular sciences · 2026Review
- Genome-wide identification and functional analysis of the WRKY transcription factor family in Reynoutria japonica reveals its role in balancing growth and abiotic stress tolerance.BMC plant biology · 2026Article
- Regulatory Role of Jasmonate Signaling in Dark-, Drought-, and Salt-Induced Leaf Senescence.International journal of molecular sciences · 2026Review
- BpWRKY6 regulates insect resistance by affecting jasmonic acid and terpenoid synthesis in Betula platyphylla.Plant biotechnology journal · 2025Article
- Unravelling the role of WRKY transcription factors in leaf senescence: Genetic and molecular insights.Journal of advanced research · 2025Review
- Gene expression through comparative transcriptome analysis unravels the molecular mechanisms of fertilizer-induced hormonal regulation and leaf senescence in maize for enhanced yield in semiarid regions.BMC plant biology · 2025Article
- Genome-Wide Identification ofGenes · 2024Article
- Thidiazuron combined with cyclanilide modulates hormone pathways and ROS systems in cotton, increasing defoliation at low temperatures.Frontiers in plant science · 2024Article
- Genome-wide identification and comprehensive analysis of WRKY transcription factor family in safflower during drought stress.Scientific reports · 2023Article
- Wheat VQ Motif-Containing Protein VQ25-A Facilitates Leaf Senescence via the Abscisic Acid Pathway.International journal of molecular sciences · 2023Article
- Transcription Factors-Regulated Leaf Senescence: Current Knowledge, Challenges and Approaches.International journal of molecular sciences · 2023Review
- Genome-Wide Identification of Sweet Orange WRKY Transcription Factors and Analysis of Their Expression in Response to Infection byCurrent issues in molecular biology · 2023Article
- Genome-Wide Identification and Expression Analysis of WRKY Transcription Factors inPlants (Basel, Switzerland) · 2023Article
- Transcriptome Analysis of Early Senescence in the Post-Anthesis Flag Leaf of Wheat (Plants (Basel, Switzerland) · 2022Article
- Analysis of Physiological and Transcriptomic Differences between a Premature Senescence Mutant (Biology · 2022Article
- Thidiazuron Promotes Leaf Abscission by Regulating the Crosstalk Complexities between Ethylene, Auxin, and Cytokinin in Cotton.International journal of molecular sciences · 2022Article
- Wounding rapidly alters transcription factor expression, hormonal signaling, and phenolic compound metabolism in harvested sugarbeet roots.Frontiers in plant science · 2022Article
- Marker-trait association analyses revealed major novel QTLs for grain yield and related traits in durum wheat.Frontiers in plant science · 2022Article
- New Advances in the Regulation of Leaf Senescence by Classical and Peptide Hormones.Frontiers in plant science · 2022Review
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLeaf senescence comprises numerous cooperative events, integrates environmental signals with age-dependent developmental cues, and coordinates the multifaceted deterioration and source-to-sink allocation of nutrients. In crops, leaf senescence has long been regarded as an essential developmental stage for productivity and quality, whereas functional characterization of candidate genes involved in the regulation of leaf senescence has, thus far, been limited in wheat.
resultsIn this study, we analyzed the expression profiles of 97 WRKY transcription factors (TFs) throughout the progression of leaf senescence in wheat and subsequently isolated a potential regulator of leaf senescence, TaWRKY42-B, for further functional investigation. By phenotypic and physiological analyses in TaWRKY42-B-overexpressing Arabidopsis plants and TaWRKY42-B-silenced wheat plants, we confirmed the positive role of TaWRKY42-B in the initiation of developmental and dark-induced leaf senescence. Furthermore, our results revealed that TaWRKY42-B promotes leaf senescence mainly by interacting with a JA biosynthesis gene, AtLOX3, and its ortholog, TaLOX3, which consequently contributes to the accumulation of JA content. In the present study, we also demonstrated that TaWRKY42-B was functionally conserved with AtWRKY53 in the initiation of age-dependent leaf senescence.
conclusionOur results revealed a novel positive regulator of leaf senescence, TaWRKY42-B, which mediates JA-related leaf senescence via activation of JA biosynthesis and has the potential to be a target gene for molecular breeding in wheat.
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