Evidence map›Paper›PMID 32993483›Full record

ArticleBMC genomics2020

Proteome of larval metamorphosis induced by epinephrine in the Fujian oyster Crassostrea angulata.

Guilan Di, Xiaohuo Xiao, Ming Him Tong, Xinhua Chen, Li Li, Miaoqin Huang, Long Zhou, Caihuan Ke

Open access · goldAbstract read
In one paragraph

Article in BMC genomics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Guilan DiState Key Laboratory of Marine Environmental Science, College of Ocean and Earth Sciences, Xiamen University, Xiamen, 361005,, China.ORCID http://orcid.org/0000-0002-3268-713X
Xiaohuo XiaoState Key Laboratory of Marine Environmental Science, College of Ocean and Earth Sciences, Xiamen University, Xiamen, 361005,, China.
Ming Him TongDepartment of Chemistry, Marine Biodiscovery Centre, the University of Aberdeen, Aberdeen, Scotland, AB24 3UE, UK.
Xinhua ChenKey Laboratory of Marine Biotechnology of Fujian Province, Institute of Oceanology, Fujian Agriculture and Forestry University, Fuzhou, 350002,, Fujian Province, China.
Li LiCollege of Fisheries, Henan Normal University, Xinxiang, 453007, China.
Miaoqin HuangState Key Laboratory of Marine Environmental Science, College of Ocean and Earth Sciences, Xiamen University, Xiamen, 361005,, China.
Long ZhouState Key Laboratory of Marine Environmental Science, College of Ocean and Earth Sciences, Xiamen University, Xiamen, 361005,, China.
Caihuan KeState Key Laboratory of Marine Environmental Science, College of Ocean and Earth Sciences, Xiamen University, Xiamen, 361005,, China. chke@xmu.edu.cn.
Xiamen University · CNFujian Agriculture and Forestry University · CNHenan Normal University · CNUniversity of Aberdeen · GB

Funding

National Marine Economic Development Demonstration Project in Xiamen 16CZB023SF12National Natural Science Foundation of China 31672651the Chinese Ministry of Science and Technology through the National Key Research and Development Program of China 2018YFD0901400The Earmarked Fund for Modern Agro-industry Technology Research System CARS-49the Key Project of Science and Technology Research of Henan Provincial Department of Education 20A240002
6 · The paper itself

Abstract

backgroundThe Fujian oyster Crassostrea angulata is an economically important species that has typical settlement and metamorphosis stages. The development of the oyster involves complex morphological and physiological changes, the molecular mechanisms of which are as yet unclear.

resultsIn this study, changes in proteins were investigated during larval settlement and metamorphosis of Crassostrea angulata using epinephrine induction. Protein abundance and identity were characterized using label-free quantitative proteomics, tandem mass spectrometry (MS/ MS), and Mascot methods. The results showed that more than 50% (764 out of 1471) of the quantified proteins were characterized as differentially expressed. Notably, more than two-thirds of the differentially expressed proteins were down-regulated in epinephrine-induced larvae. The results showed that "metabolic process" was closely related to the development of settlement and metamorphosis; 5 × 10

conclusionThe study provides insight into proteins that function in energy metabolism, immune responses, settlement and metamorphosis, and shell formation in C. angulata. The results contribute valuable information for further research on larval settlement and metamorphosis.

Indexed as

Metamorphosis, BiologicalAnimalsCalmodulinCalreticulinCrassostreaCytoskeletonEpinephrineLarvaMitogen-Activated Protein KinasesProteomeCalmodulinCalreticulinEpinephrineMitogen-Activated Protein KinasesProteomeCrassostrea angulataEpinephrineMetamorphosisProteomicSettlement

Identifiers

PMID32993483
PMCPMC7525975
OpenAlexW3090196928

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.