Evidence map›Paper›PMID 32993292›Full record

ArticleLangmuir : the ACS journal of surfaces and colloids2020

DOTA Glycodendrimers as Cu(II) Complexing Agents and Their Dynamic Interaction Characteristics toward Liposomes.

Marianna Carone, Silvia Moreno, Michela Cangiotti, Maria Francesca Ottaviani, Peng Wang, Riccardo Carloni, Dietmar Appelhans

Open access · hybridAbstract read
In one paragraph

Article in Langmuir : the ACS journal of surfaces and colloids, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Marianna CaroneDepartment of Chemistry and Biochemistry, University of Bern, 3012 Bern, Switzerland.
Silvia MorenoLeibniz Institute of Polymer Research Dresden, Hohe Strasse 6, D-01069 Dresden, Germany.
Michela CangiottiDepartment of Pure and Applied Sciences, Università degli studi di Urbino "Carlo Bo", Urbino 61029, Italy.
Maria Francesca OttavianiDepartment of Pure and Applied Sciences, Università degli studi di Urbino "Carlo Bo", Urbino 61029, Italy.ORCID 0000-0002-4681-4718
Peng WangLeibniz Institute of Polymer Research Dresden, Hohe Strasse 6, D-01069 Dresden, Germany.
Riccardo CarloniDepartment of Pure and Applied Sciences, Università degli studi di Urbino "Carlo Bo", Urbino 61029, Italy.ORCID 0000-0001-8052-213X
Dietmar AppelhansLeibniz Institute of Polymer Research Dresden, Hohe Strasse 6, D-01069 Dresden, Germany.ORCID 0000-0003-4611-8963
Leibniz Institute of Polymer Research · DEUniversity of Urbino · ITUniversity of Bern · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Copper (Cu)(II) ions, mainly an excess amount, play a negative role in the course of several diseases, like cancers, neurodegenerative diseases, and the so-called Wilson disease. On the contrary, Cu(II) ions are also capable of improving anticancer drug efficiency. For this reason, it is of great interest to study the interacting ability of Cu(II)-nanodrug and Cu(II)-nanocarrier complexes with cell membranes for their potential use as nanotherapeutics. In this study, the complex interaction between 1,4,7,10-tetraazacyclododecan-N,N',N'',N'''-tetraacetic acid (DOTA)-functionalized poly(propyleneimine) (PPI) glycodendrimers and Cu(II) ions and/or neutral and anionic lipid membrane models using different liposomes is described. These interactions were investigated

Indexed as

LiposomesMembrane FluidityElectron Spin Resonance SpectroscopyHydrophobic and Hydrophilic InteractionsLipid BilayersLipid BilayersLiposomes

Identifiers

PMID32993292
PMCPMC8015221
OpenAlexW3089654583

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.