Evidence map›Paper›PMID 32993279›Full record

ArticleAnatomy & cell biology2020

Role of cerebrospinal fluid in differentiation of human dental pulp stem cells into neuron-like cells.

Ghazaleh Goudarzi, Hatef Ghasemi Hamidabadi, Maryam Nazm Bojnordi, Azim Hedayatpour, Ali Niapour, Maria Zahiri, Forouzan Absalan, Shahram Darabi

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Anatomy & cell biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

Ghazaleh GoudarziDepartment of Brain and Cognitive Sciences, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran.ORCID https://orcid.org/0000-0002-0421-1767
Hatef Ghasemi HamidabadiDepartment of Anatomy & Cell Biology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.ORCID https://orcid.org/0000-0002-2178-6503
Maryam Nazm BojnordiDepartment of Anatomy & Cell Biology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.ORCID https://orcid.org/0000-0003-1176-2417
Azim HedayatpourDepartment of Anatomy, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0002-1036-0697
Ali NiapourResearch Laboratory for Embryology and Stem Cells, Department of Anatomical Sciences, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran.ORCID https://orcid.org/0000-0002-9013-4664
Maria ZahiriDepartment of Anatomical Sciences, School of Medical Sciences, Bushehr University of Medical Sciences, Bushehr, Iran.ORCID https://orcid.org/0000-0003-2978-0349
Forouzan AbsalanAbadan School of Medical Sciences, Abadan, Iran.ORCID https://orcid.org/0000-0002-7875-0173
Shahram DarabiCellular and Molecular Research Center, Qazvin University of Medical Sciences, Qazvin, Iran.ORCID https://orcid.org/0000-0002-9405-6640
Mazandaran University of Medical Sciences · IRArdabil University of Medical Sciences · IRBushehr University of Medical Sciences · IRQazvin University of Medical Sciences · IRRoyan Institute · IRTehran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human dental pulp stem cells (hDPSCs) could be differentiated into neuron like-cells under particular microenvironments. It has been reported that a wide range of factors, presented in cerebrospinal fluid (CSF), playing part in neuronal differentiation during embryonic stages, we herein introduce a novel culture media complex to differentiate hDPSCs into neuron-like cells. The hDPSCs were initially isolated and characterized. The CSF was prepared from the Cisterna magna of 19-day-old Wistar rat embryos, embryonic cerebrospinal fluid (E-CSF). The hDPSCs were treated by 5% E-CSF for 2 days, then neurospheres were cultured in DMEM/F12 supplemented with 10

Indexed as

AlzheimerCell transdifferentiationCerebrospinal fluidHuman dental pulp stem cells

Identifiers

PMID32993279
PMCPMC7527124
OpenAlexW3090149623

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.