ArticlePolymers2020
Comparison of Scaffolds Fabricated via 3D Printing and Salt Leaching: In Vivo Imaging, Biodegradation, and Inflammation.
Article in Polymers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
13 citing papers in PubMed, 21 citations in OpenAlex.
- Triazine-Trione Thermosets with High Processability for Scaffold Applications in Bone Tissue Engineering.Advanced healthcare materials · 2026Article
- Hyaluronic acid-coated Poly(L-lactide-co-1,3-trimethylene carbonate) modulate early cellular-scaffold interactions and osteogenic potential: a comprehensiveFrontiers in bioengineering and biotechnology · 2026Article
- Bone Regeneration in Rat Calvaria Using 3D-Printed Scaffolds with Graded Porosity and In Vitro Degradation.ACS omega · 2025Article
- Biodegradable Polyesters: Approaches to Increase Degradation Rates for Biomedical Applications.ACS macro letters · 2025Review
- 3D digital light process bioprinting: Cutting-edge platforms for resolution of organ fabrication.Materials today. Bio · 2024Review
- 3D-printed thermally expanded monolithic foam for solid-phase extraction of multiple trace metals.Mikrochimica acta · 2024Article
- Tracheal Tissue Engineering: Principles and State of the Art.Bioengineering (Basel, Switzerland) · 2024Review
- Article
- 3D printed PCLA scaffold with nano-hydroxyapatite coating doped green tea EGCG promotes bone growth and inhibits multidrug-resistant bacteria colonization.Cell proliferation · 2022Article
- Functionalized Electrospun Scaffold-Human-Muscle-Derived Stem Cell Construct Promotes In Vivo Neocartilage Formation.Polymers · 2022Article
- Article
- Scaffold printing using biodegradable poly(1,4-butylene carbonate) ink: printability,Materials today. Bio · 2021Article
- Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
In this work, we prepared fluorescently labeled poly(ε-caprolactone-ran-lactic acid) (PCLA-F) as a biomaterial to fabricate three-dimensional (3D) scaffolds via salt leaching and 3D printing. The salt-leached PCLA-F scaffold was fabricated using NaCl and methylene chloride, and it had an irregular, interconnected 3D structure. The printed PCLA-F scaffold was fabricated using a fused deposition modeling printer, and it had a layered, orthogonally oriented 3D structure. The printed scaffold fabrication method was clearly more efficient than the salt leaching method in terms of productivity and repeatability. In the in vivo fluorescence imaging of mice and gel permeation chromatography of scaffolds removed from rats, the salt-leached PCLA scaffolds showed slightly faster degradation than the printed PCLA scaffolds. In the inflammation reaction, the printed PCLA scaffolds induced a slightly stronger inflammation reaction due to the slower biodegradation. Collectively, we can conclude that in vivo biodegradability and inflammation of scaffolds were affected by the scaffold fabrication method.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.