ArticleAnimals : an open access journal from MDPI2020
Local Anesthesia in Piglets Undergoing Castration-A Comparative Study to Investigate the Analgesic Effects of Four Local Anesthetics Based on Defensive Behavior and Side Effects.
Article in Animals : an open access journal from MDPI, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 22 citations in OpenAlex.
- Two restraining devices in connection to surgical castration with or without local anesthesia: effects on piglet stress.Porcine health management · 2025Article
- Behavior of Piglets in an Observation Arena before and after Surgical Castration with Local Anesthesia.Animals : an open access journal from MDPI · 2023Article
- Sutureless Technique for Surgical Castration in Adult Boars: A Feasibility Study.Animals : an open access journal from MDPI · 2023Article
- Efficacy of inguinal buffered lidocaine and intranasal flunixin meglumine on mitigating physiological and behavioral responses to pain in castrated piglets.Frontiers in pain research (Lausanne, Switzerland) · 2023Article
- Comparative Study of Pain-Related Responses of Male Piglets up to Seven Days of Age to the Application of Different Local Anaesthetics and Subsequent Castration.Animals : an open access journal from MDPI · 2022Article
- Welfare of pigs on farm.EFSA journal. European Food Safety Authority · 2022Article
- Evaluation of Two Injection Techniques in Combination with the Local Anesthetics Lidocaine and Mepivacaine for Piglets Undergoing Surgical Castration.Animals : an open access journal from MDPI · 2022Article
- Piglets' acute responses to local anesthetic injection and surgical castration: Effects of the injection method and interval between injection and castration.Frontiers in veterinary science · 2022Article
- Piglets' acute responses to procaine-based local anesthetic injection and surgical castration: Effects of two volumes of anesthetic.Frontiers in pain research (Lausanne, Switzerland) · 2022Article
- The Neuroimmune Interface and Chronic Pain Through the Lens of Production Animals.Frontiers in neuroscience · 2022Review
- Facile design of lidocaine-loaded polymeric hydrogel to persuade effects of local anesthesia drug delivery system: completeDrug delivery · 2021Article
- Efficacy of Intra-Operative Topical Wound Anaesthesia to Mitigate Piglet Castration Pain-A Large, Multi-Centred Field Trial.Animals : an open access journal from MDPI · 2021Article
Corrections and comments
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Authors and funding
16 authors at 2 institutions in 1 country.
Funding
Abstract
The aim of the present study was to investigate the effect of four local anesthetics on pain relief during surgical castration under standardized conditions in conscious piglets. Therefore, 71 male piglets (three to seven days) were distributed into control groups (handling, castration without anesthesia or analgesia) and local anesthetic trial groups (procaine, lidocaine, bupivacaine, mepivacaine). Then, 20 min prior to castration, animals of the treatment groups, except piglets in the handling group, received an injection of a local anesthetic or sodium chloride of 0.5 mL intratesticularly and 0.5 mL subscrotally. During injection and castration, defensive behavior was evaluated. Locomotor activity, as well as postoperative bleeding, wound healing and average daily weight gain were assessed to detect side effects. The injection caused increased defensive movements, significantly in the bupivacaine group. Lidocaine and mepivacaine significantly reduced defensive movements during castration, and procaine and bupivacaine only during severing of the spermatic cord. Impairments of locomotor activity were found in piglets injected with lidocaine, bupivacaine or sodium chloride. Considering healing, bleeding and weight gain, no negative impacts were observed. In conclusion, lidocaine and mepivacaine were able to achieve significant pain relief during the castration procedure, whereas procaine and bupivacaine only during the severing of the spermatic cord. Moreover, the injection of bupivacaine seemed to be painful itself.
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