ArticleJournal of clinical medicine2020
Health-Related Quality of Life in Male Patients under Treatment for Substance Use Disorders with and without Major Depressive Disorder: Influence in Clinical Course at One-Year Follow-Up.
Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 28 citations in OpenAlex.
- Patterns of Psychiatric Comorbidity Among Drug Users: A Prospective Observational Study in a Romanian Psychiatric Hospital.Healthcare (Basel, Switzerland) · 2025Article
- Examining quality of life by recovery status among college students with a history of substance use.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- Health-related quality of life in psychiatric outpatients: a cross-sectional study of associations with symptoms, diagnoses, and employment status.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024Article
- Quality of Life Assessment Using the WHOQOL-BREF Survey in Hospitalized Patients with Alcohol Use Disorder from Romania.Diseases (Basel, Switzerland) · 2024Article
- Prevalence and Correlates of Depression and Bipolar Disorder Among Patients Maintained on Methadone and Buprenorphine in Ukraine.International journal of mental health and addiction · 2024Article
- Personality correlates of past-year alcohol use in individuals with severe alcohol use disorder and a lifetime history of involvement in alcoholics anonymous.Alcohol, clinical & experimental research · 2024Article
- The impact of methamphetamine on psychosocial variables in patients from Iraq.Frontiers in psychiatry · 2024Article
- Abstinence duration and psychopathology among addiction outpatients during 18 months of COVID-19.Frontiers in psychiatry · 2024Article
- Not Two Sides of the Same Coin: A Qualitative Comparative Analysis of Post-Treatment Abstinence and Relapse.Substance abuse and rehabilitation · 2024Article
- Sociodemographic factors and use of pain medication are associated with health-related quality of life: results from an adult community mental health service in Norway.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023Article
- Design, implementation and preliminary results of a type-2 hybrid cluster-randomized trial of integrating screening and treatment for major depressive disorder into specialty clinics providing opioid agonist therapies in Ukraine.Contemporary clinical trials · 2023Article
- Factors associated with medication interruption among outpatients with severe mental illness exposed to COVID-19.Frontiers in public health · 2023Article
- Healthy Habits Factors and Stress Associated with Health-Related Quality of Life in a Peruvian Adult Population: A Cross-Sectional Study.Journal of multidisciplinary healthcare · 2023Article
- Establishing a System of Care for Severe and Refractory Dual Disorder in the State of Hawai'i.Hawai'i journal of health & social welfare · 2022Review
- Protocol for Characterization of Addiction and Dual Disorders: Effectiveness of Coadjuvant Chronotherapy in Patients with Partial Response.Journal of clinical medicine · 2022Article
- Health-related quality of life in outpatients with substance use disorder: evolution over time and associated factors.Health and quality of life outcomes · 2022Article
- Special Issue: Diagnosis and Management of Addiction and Other Mental Disorders (Dual Disorders).Journal of clinical medicine · 2021Article
- Circadian Functioning and Quality of Life in Substance Use Disorder Patients With and Without Comorbid Major Depressive Disorder.Frontiers in psychiatry · 2021Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Health-related quality of life (HRQoL) assessment has interest as an indicator of degree of affectation and prognosis in mental disorders. HRQoL is impaired in both Substance Use Disorder (SUD) and Major Depressive Disorder (MDD), two conditions highly prevalent, although less studied when both are coexisting (SUD + MDD). Hence, we decided to explore HRQoL with the SF-36 survey in a sample of 123 SUD and 114 SUD + MDD patients (51 symptomatic and 63 asymptomatic of depressive symptoms) under treatment. We performed analyses to examine HRQoL among groups, and its predictive value at 3-, 6- and 12-month follow-ups through regression models. Patients with SUD + MDD had worse HRQoL than SUD patients and population norms. For Mental Health, Vitality, and General Health dimensions, lower scores were observed for SUD + MDD regardless the presence/absence of depressive symptoms. For Physical Functioning and Health Change, depressive symptomatology and not the comorbidity of SUD + MDD diagnoses explained HRQoL limitations. At 3-, 6- and 12-month follow-ups we observed two predictors of relapses, General Health for asymptomatic SUD + MDD, and Physical Functioning for SUD. Improving HRQoL in SUD + MDD may be targeted during patient's treatment; future studies should explore the influence of HRQoL on patient's prognosis taking into account the presence/absence of depressive symptomatology.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.