Evidence map›Paper›PMID 32992971›Full record

ArticleBiomedicines2020

Non-Adherence to Statin Treatment in Older Patients with Peripheral Arterial Disease Depending on Persistence Status.

Martin Wawruch, Gejza Wimmer, Jan Murin, Martina Paduchova, Miriam Petrova, Tomas Tesar, Petra Matalova, Beata Havelkova, Michal Trnka, Emma Aarnio

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Martin WawruchInstitute of Pharmacology and Clinical Pharmacology, Faculty of Medicine, Comenius University, 811 08 Bratislava, Slovakia.ORCID 0000-0001-7672-1574
Gejza WimmerInstitute of Measurement Science, Slovak Academy of Sciences, 841 04 Bratislava, Slovakia.
Jan Murin1st Department of Internal Medicine, Faculty of Medicine, Comenius University, 813 69 Bratislava, Slovakia.
Martina PaduchovaDepartment of Angiology, Health Centre, 917 01 Trnava, Slovakia.
Miriam PetrovaInstitute of Pharmacology and Clinical Pharmacology, Faculty of Medicine, Comenius University, 811 08 Bratislava, Slovakia.
Tomas TesarDepartment of Organisation and Management of Pharmacy, Faculty of Pharmacy, Comenius University, 832 32 Bratislava, Slovakia.
Petra MatalovaDepartment of Pharmacology, Faculty of Medicine and Dentistry, Palacky University, 775 15 Olomouc, Czech Republic.
Beata HavelkovaGeneral Health Insurance Company, 851 04 Bratislava, Slovakia.
Michal TrnkaInstitute of Medical Physics, Biophysics, Informatics and Telemedicine, Faculty of Medicine, Comenius University, 813 72 Bratislava, Slovakia.ORCID 0000-0003-4599-1971
Emma AarnioInstitute of Biomedicine, University of Turku, 20014 Turku, Finland.
Comenius University Bratislava · SKPalacký University Olomouc · CZSlovak Academy of Sciences · SKUniversity of Turku · FI

Funding

Vedecká Grantová Agentúra MŠVVaŠ SR a SAV VEGA 1/0024/21
6 · The paper itself

Abstract

The effectiveness of statins in secondary prevention of peripheral arterial disease (PAD) largely depends on patients' adherence to treatment. The aims of our study were: (a) to analyze non-adherence during the whole follow-up in persistent patients, and only during persistence for non-persistent patients; (b) to identify factors associated with non-adherence separately among persistent and non-persistent patients. A cohort of 8330 statin users aged ≥65 years, in whom PAD was newly diagnosed between January 2012-December 2012, included 5353 patients persistent with statin treatment, and 2977 subjects who became non-persistent during the 5-year follow-up. Non-adherence was defined using the proportion of days covered <80%. Patient- and statin-related characteristics associated with non-adherence were identified with binary logistic regression. A significantly higher proportion of non-adherent patients was found among non-persistent patients compared to persistent subjects (43.6% vs. 29.6%;

Indexed as

non-adherenceperipheral arterial diseasepolypharmacyrisk factorsstatins

Identifiers

PMID32992971
PMCPMC7599852
OpenAlexW3088088731

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.