Evidence map›Paper›PMID 32992921›Full record

ArticleInternational journal of molecular sciences2020

Silver Nanoparticles Protect Skin from Ultraviolet B-Induced Damage in Mice.

Yu-Yi Ho, Der-Shan Sun, Hsin-Hou Chang

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Nanoparticles as a Therapeutic Delivery System for Skin Cancer Prevention and Treatment.JID innovations : skin science from molecules to population health · 2023
    Review
  6. Article
  7. Article
  8. Article
  9. Construction of a Secondary Enclosure for UVB Irradiation of Mice.JID innovations : skin science from molecules to population health · 2023
    Article
  10. NovelPharmaceuticals (Basel, Switzerland) · 2022
    Article
  11. Article
  12. Heat-KilledAntioxidants (Basel, Switzerland) · 2022
    Article
  13. Article
  14. Review
  15. Metal Nano/Microparticles for Bioapplications.International journal of molecular sciences · 2021
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Yu-Yi HoDepartment of Molecular Biology and Human Genetics, Tzu-Chi University, Hualien 97004, Taiwan.
Der-Shan SunDepartment of Molecular Biology and Human Genetics, Tzu-Chi University, Hualien 97004, Taiwan.
Hsin-Hou ChangDepartment of Molecular Biology and Human Genetics, Tzu-Chi University, Hualien 97004, Taiwan.ORCID 0000-0002-8731-3485
Tzu Chi University · TW

Funding

Ministry of Science and Technology, Taiwan 105-2923-B-320-001-MY3Ministry of Science and Technology, Taiwan 107-2311-B-320-002-MY3Tzu-Chi Medical Foundation TCMMP104-06Tzu-Chi Medical Foundation TCMMP108-04
6 · The paper itself

Abstract

Ultraviolet (UV) radiation from sunlight has various adverse effects; thus, UV blockage is recommended for preventing sunburn. Common sunscreen ingredients, such as nanosized titanium dioxide and zinc oxide, offer effective protection and enhance cosmetic appearance; however, health concerns have been raised regarding their photocatalytic activity, which generates reactive oxygen species under UV illumination. Silver nanoparticles (AgNPs) are known as safe materials for use in a wide spectrum of biomedical applications. In vitro studies have revealed that AgNPs may have a protective effect against UV irradiation, but the effects in animal studies remain unclear. The present study demonstrated that AgNPs effectively protect against UVB-induced skin damage both in cell cultures and mouse models. These results suggested that AgNPs are feasible and safe as sunscreen ingredients for protection against UVB-induced skin damage.

Indexed as

Metal NanoparticlesAnimalsHaCaT CellsHumansMaleMiceMice, Inbred C57BLSilverSkinSunlightSunscreening AgentsUltraviolet RaysSilverSunscreening Agentscell deathinflammationinterleukin-1reactive oxygen speciessilver nanoparticlesskin damagesunburnsunscreentitanium dioxideultraviolet B

Identifiers

PMID32992921
PMCPMC7582269
OpenAlexW3088430071

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.