Evidence map›Paper›PMID 32992843›Full record

ArticleAntioxidants (Basel, Switzerland)2020

Sex and SP-A2 Dependent NAD(H) Redox Alterations in Mouse Alveolar Macrophages in Response to Ozone Exposure: Potential Implications for COVID-19.

He N Xu, Zhenwu Lin, Chintan K Gandhi, Shaili Amatya, Yunhua Wang, Lin Z Li, Joanna Floros

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.5field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. ROS and COVID.Antioxidants (Basel, Switzerland) · 2022
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

He N XuBritton Chance Laboratory of Redox Imaging, Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0001-5127-2629
Zhenwu LinBritton Chance Laboratory of Redox Imaging, Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Chintan K GandhiDepartment of Pediatrics, Center for Host Defense, Inflammation, and Lung disease, The Pennsylvania State University College of Medicine, Hershey, PA 17033, USA.
Shaili AmatyaDepartment of Pediatrics, Center for Host Defense, Inflammation, and Lung disease, The Pennsylvania State University College of Medicine, Hershey, PA 17033, USA.
Yunhua WangDepartment of Pediatrics, Center for Host Defense, Inflammation, and Lung disease, The Pennsylvania State University College of Medicine, Hershey, PA 17033, USA.
Lin Z LiBritton Chance Laboratory of Redox Imaging, Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0001-9447-7982
Joanna FlorosDepartments of Pediatric and Obstetrics and Gynecology, College of Medicine Pennsylvania State University, Hershey, PA 17033, USA.
Pennsylvania State University · USUniversity of Pennsylvania · US

Funding

Redox imaging for breast cancer prognosisR01CA191207 · NCI · UNIVERSITY OF PENNSYLVANIA · PI LI, LIN Z · 2015 to 2019
$3.2M
Department of Pediatrics, Pennsylvania State University College of Medicine CHILD Research FundNCI NIH HHS R01 CA191207NIH HHS R01CA191207
6 · The paper itself

Abstract

Co-enzyme nicotinamide adenine dinucleotide (NAD(H)) redox plays a key role in macrophage function. Surfactant protein (SP-) A modulates the functions of alveolar macrophages (AM) and ozone (O

Indexed as

innate immunitylungmacrophage activationnicotinamide adenine dinucleotide (NAD(H))optical redox imagingoxidized flavoprotein containing flavin adenine dinucleotide (FAD)ozoneredox heterogeneityredox ratiosurfactant protein Asurfactant protein A2 (SP-A2)

Identifiers

PMID32992843
PMCPMC7601279
OpenAlexW3087985975

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.