ArticleJournal of clinical medicine2020
Diffusional Kurtosis Imaging of White Matter Degeneration in Glaucoma.
Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- Application of advanced diffusion MRI based tractometry of the visual pathway in glaucoma: a systematic review.Frontiers in neuroscience · 2025Pooled it
- Altered amplitudes of low-frequency fluctuations in primary open angle glaucoma patients: a resting-state fMRI study.International journal of ophthalmology · 2026Article
- White-matter alterations in dysthyroid optic neuropathy: a diffusion kurtosis imaging study using tract-based spatial statistics.Japanese journal of radiology · 2025Article
- Altered static and dynamic functional network connectivity in primary angle-closure glaucoma patients.Scientific reports · 2024Article
- Arterial spin labeling reveals disordered cerebral perfusion and cerebral blood flow-based functional connectivity in primary open-angle glaucoma.Brain imaging and behavior · 2024Article
- Diffusion tensor imaging of optic neuropathies: a narrative review.Quantitative imaging in medicine and surgery · 2024Review
- MRI and Clinical Biomarkers Overlap between Glaucoma and Alzheimer's Disease.International journal of molecular sciences · 2023Review
- Atypical responses to faces during binocular rivalry in early glaucoma.Frontiers in neuroscience · 2023Article
- Editorial: New perspectives in glaucoma pathophysiology, diagnosis, and treatment.Frontiers in medicine · 2023Article
- Advanced Diffusion MRI of the Visual System in Glaucoma: From Experimental Animal Models to Humans.Biology · 2022Review
- Application of advanced magnetic resonance imaging in glaucoma: a narrative review.Quantitative imaging in medicine and surgery · 2022Review
- Combined use of coenzyme Q10 and citicoline: A new possibility for patients with glaucoma.Frontiers in medicine · 2022Review
- Altered functional connectivity of the thalamus in primary angle-closure glaucoma patients: A resting-state fMRI study.Frontiers in neurology · 2022Article
- Perceptual Grouping During Binocular Rivalry in Mild Glaucoma.Frontiers in aging neuroscience · 2022Article
- Diffusion Tensor Imaging of Visual Pathway Abnormalities in Five Glaucoma Animal Models.Investigative ophthalmology & visual science · 2021Article
- Disrupted Topological Organization of the Brain Structural Network in Patients With Thyroid-Associated Ophthalmopathy.Investigative ophthalmology & visual science · 2021Article
- Demyelination of the Optic Nerve: An Underlying Factor in Glaucoma?Frontiers in aging neuroscience · 2021Review
Corrections and comments
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Authors and funding
15 authors at 2 institutions in 3 countries.
Funding
Abstract
Glaucoma is an optic neuropathy characterized by death of retinal ganglion cells and loss of their axons, progressively leading to blindness. Recently, glaucoma has been conceptualized as a more diffuse neurodegenerative disorder involving the optic nerve and also the entire brain. Consistently, previous studies have used a variety of magnetic resonance imaging (MRI) techniques and described widespread changes in the grey and white matter of patients. Diffusion kurtosis imaging (DKI) provides additional information as compared with diffusion tensor imaging (DTI), and consistently provides higher sensitivity to early microstructural white matter modification. In this study, we employ DKI to evaluate differences among healthy controls and a mixed population of primary open angle glaucoma patients ranging from stage I to V according to Hodapp-Parrish-Anderson visual field impairment classification. To this end, a cohort of patients affected by primary open angle glaucoma (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.