ArticleBrain sciences2020
Participatory Art Activities Increase Salivary Oxytocin Secretion of ASD Children.
Article in Brain sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Art-based interventions and social-emotional outcomes in children with autism spectrum disorder: a systematic review and meta-analysis with a proposed neurodevelopmental framework.Frontiers in human neuroscience · 2026Pooled it
- A comparison between children and adolescents with autism spectrum disorders and healthy controls in biomedical factors, trace elements, and microbiota biomarkers: a meta-analysis.Frontiers in psychiatry · 2023Pooled it
- Differences in Oxytocin Response Between a Group of Friends and a Group of Strangers Following Facilitated Drum Circle Activities.Brain and behavior · 2026Article
- Salivary oxytocin responses to infant stimuli vary by EPDS scores among postpartum Japanese mothers without clinically diagnosed postpartum depression.Frontiers in endocrinology · 2025Article
- Wonder symphony: epigenetics and the enchantment of the arts.Environmental epigenetics · 2024Review
- Exploratory study to examine the neuroendocrinological changes in typically developing adults during a music-related participatory practice using computer software.Frontiers in psychology · 2024Article
- Endogenous oxytocin levels in children with autism: Associations with cortisol levels and oxytocin receptor gene methylation.Translational psychiatry · 2023Article
- Oral Supplementation with Maca Improves Social Recognition Deficits in the Valproic Acid Animal Model of Autism Spectrum Disorder.Brain sciences · 2023Article
- Infant Stimulation Induced a Rapid Increase in Maternal Salivary Oxytocin.Brain sciences · 2022Article
- Endogenous Oxytocin Levels in Autism-A Meta-Analysis.Brain sciences · 2021Review
- Oxytocin-Trust Link in Oxytocin-Sensitive Participants and Those Without Autistic Traits.Frontiers in neuroscience · 2021Article
- The Challenging Heterogeneity of Autism: Editorial for Brain Sciences Special Issue "Advances in Autism Research".Brain sciences · 2020Article
Corrections and comments
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Authors and funding
12 authors at 4 institutions in 2 countries.
Funding
Abstract
Autism spectrum disorder (ASD) occurs in 1 in 160 children worldwide. Individuals with ASD tend to be unique in the way that they comprehend themselves and others, as well as in the way that they interact and socialize, which can lead to challenges with social adaptation. There is currently no medication to improve the social deficit of children with ASD, and consequently, behavioral and complementary/alternative intervention plays an important role. In the present pilot study, we focused on the neuroendocrinological response to participatory art activities, which are known to have a positive effect on emotion, self-expression, sociability, and physical wellbeing. We collected saliva from 12 children with ASD and eight typically developed (TD) children before and after a visual art-based participatory art workshop to measure the levels of oxytocin, a neuropeptide involved in a wide range of social behaviors. We demonstrated that the rate of increase in salivary oxytocin following art activities in ASD children was significantly higher than that in TD children. In contrast, the change rate of salivary cortisol after participatory art activities was similar between the two groups. These results suggest that the beneficial effects of participatory art activities may be partially mediated by oxytocin release, and may have therapeutic potential for disorders involving social dysfunction.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.