Evidence map›Paper›PMID 32992503›Full record

ArticleCancers2020

Identification of Genes Whose Expression Overlaps Age Boundaries and Correlates with Risk Groups in Paediatric and Adult Acute Myeloid Leukaemia.

Lindsay Davis, Ken I Mills, Kim H Orchard, Barbara-Ann Guinn

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Molecular Mechanisms and Therapies of Myeloid Leukaemia.International journal of molecular sciences · 2022
    Article
  6. Increasing Role of Targeted Immunotherapies in the Treatment of AML.International journal of molecular sciences · 2022
    Review
  7. Characterization ofBiomolecules · 2021
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Lindsay DavisPatrick G. Johnson Centre for Cancer Research, Queen's University Belfast, Lisburn Road, Belfast BT9 7AE, UK.
Ken I MillsPatrick G. Johnson Centre for Cancer Research, Queen's University Belfast, Lisburn Road, Belfast BT9 7AE, UK.
Kim H OrchardDepartment of Haematology, University Hospital Southampton NHS Foundation Trust, Tremona Road, Southampton SO16 6YD, UK.
Barbara-Ann GuinnDepartment of Biomedical Sciences, University of Hull, Cottingham Road, Kingston-upon-Hull HU6 7RX, UK.ORCID 0000-0003-0639-4541
Queen's University Belfast · GBUniversity Hospital Southampton NHS Foundation Trust · GBUniversity of Hull · GB

Funding

Leukaemia and Lymphoma NI : R2536CNR
6 · The paper itself

Abstract

Few studies have compared gene expression in paediatric and adult acute myeloid leukaemia (AML). In this study, we have analysed mRNA-sequencing data from two publicly accessible databases: (1) National Cancer Institute's Therapeutically Applicable Research to Generate Effective Treatments (NCI-TARGET), examining paediatric patients, and (2) The Cancer Genome Atlas (TCGA), examining adult patients with AML. With a particular focus on 144 known tumour antigens, we identified

Indexed as

antigen identificationHOXmeta-analysismRNA-sequencingpaediatric and adult acute myeloid leukaemiaSOXWNT

Identifiers

PMID32992503
PMCPMC7650662
OpenAlexW3088528983

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.